Imprinted Small RNAs Unraveled: Maternal MicroRNAs Antagonize a Paternal-Genome-Driven Gene Expression Network

Amani Ghousein; Robert Feil

doi:10.1016/J.MOLCEL.2020.03.019

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Imprinted Small RNAs Unraveled: Maternal MicroRNAs Antagonize a Paternal-Genome-Driven Gene Expression Network

Journal article

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Imprinted Small RNAs Unraveled: Maternal MicroRNAs Antagonize a Paternal-Genome-Driven Gene Expression Network

Amani Ghousein and Robert Feil

Molecular Cell, Vol.78(1), pp.3-5

04/2020

DOI: https://doi.org/10.1016/J.MOLCEL.2020.03.019

PMID: 32243830

Abstract

Gene Regulatory Networks

Genome

Genomic Imprinting

MicroRNAs

Neurons

Whipple et al., 2020 describe that, in neurons, a dense cluster of maternally expressed microRNAs post-transcriptionally downregulates several imprinted genes expressed from the paternal genome-an antagonistic mechanism that modulates neuronal functions and provides insights into the evolution of genomic imprinting.

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Title: Imprinted Small RNAs Unraveled: Maternal MicroRNAs Antagonize a Paternal-Genome-Driven Gene Expression Network
Creators - without role: Amani Ghousein - Université de Montpellier, Institut de Génétique Moléculaire de Montpellier - IGMM
Robert Feil - Université de Montpellier, Institut de Génétique Moléculaire de Montpellier - IGMM
Publication Details: Molecular Cell, Vol.78(1), pp.3-5
Identifiers: 9938999409311
Academic Unit: Institut de Génétique Moléculaire de Montpellier - IGMM
Language: English
Resource Type: Journal article
Local Fields: hal-02531742