Implications of insecticide resistance for malaria vector control with long-lasting insecticidal nets: trends in pyrethroid resistance during a WHO-coordinated multi-country prospective study

Jackie Cook; Sean Tomlinson; Immo Kleinschmidt; Martin James Donnelly; Martin Akogbeto; Alioun Adechoubou; Achile Massougbodji; Mariam Oke-Sopoh; Vincent Corbel; Sylvie Cornelie; Aurore Ogouyemi-Hounto; Josiane Etang; Herman Parfait Awono-Ambene; Jude Bigoga; Stanislas Elysee Mandeng; Boris Njeambosay; Raymond Tabue; Celestin Kouambeng; Etienne Fondjo; Kamaraju Raghavendra; Rajendra M. Bhatt; Mehul Kumar Chourasia; Dipak K. Swain; Sreehari Uragayala; Neena Valecha; Charles Mbogo; Nabie Bayoh; Teresa Kinyari; Kiambo Njagi; Lawrence Muthami; Luna Kamau; Evan Mathenge; Eric Ochomo; Hmooda Toto Kafy; Bashir Adam Ismail; Elfatih M. Malik; Khalid Elmardi; Jihad Eltaher Sulieman; Mujahid Abdin; Krishanthi Subramaniam; Brent Thomas; Philippa West; John Bradley; Tessa Bellamy Knox; Abraham Peter Mnzava; Jonathan Lines; Michael Macdonaldand; Zinga Jose Nkuni; Kenya Study Team

doi:10.1186/s13071-018-3101-4

Retour

Implications of insecticide resistance for malaria vector control with long-lasting insecticidal nets: trends in pyrethroid resistance during a WHO-coordinated multi-country prospective study

Article de revue

Avec comité de lecture

Implications of insecticide resistance for malaria vector control with long-lasting insecticidal nets: trends in pyrethroid resistance during a WHO-coordinated multi-country prospective study

Jackie Cook, Sean Tomlinson, Immo Kleinschmidt, Martin James Donnelly, Martin Akogbeto, Alioun Adechoubou, Achile Massougbodji, Mariam Oke-Sopoh, Vincent Corbel, Sylvie Cornelie, …

Parasites & vectors, Vol.11(1), pp.550-550

22/10/2018

DOI: https://doi.org/10.1186/s13071-018-3101-4

PMID: 30348209

Résumé

Life Sciences & Biomedicine

Parasitology

Science & Technology

Tropical Medicine

BackgroundIncreasing pyrethroid resistance has been an undesirable correlate of the rapid increase in coverage of insecticide-treated nets (ITNs) since 2000. Whilst monitoring of resistance levels has increased markedly over this period, longitudinal monitoring is still lacking, meaning the temporal and spatial dynamics of phenotypic resistance in the context of increasing ITN coverage are unclear.MethodsAs part of a large WHO-co-ordinated epidemiological study investigating the impact of resistance on malaria infection, longitudinal monitoring of phenotypic resistance to pyrethroids was undertaken in 290 clusters across Benin, Cameroon, India, Kenya and Sudan. Mortality in response to pyrethroids in the major anopheline vectors in each location was recorded during consecutive years using standard WHO test procedures. Trends in mosquito mortality were examined using generalised linear mixed-effect models.ResultsInsecticide resistance (using the WHO definition of mortality < 90%) was detected in clusters in all countries across the study period. The highest mosquito mortality (lowest resistance frequency) was consistently reported from India, in an area where ITNs had only recently been introduced. Substantial temporal and spatial variation was evident in mortality measures in all countries. Overall, a trend of decreasing mosquito mortality (increasing resistance frequency) was recorded (Odds Ratio per year: 0.79 per year (95% CI: 0.79-0.81, P < 0.001). There was also evidence that higher net usage was associated with lower mosquito mortality in some countries.DiscussionPyrethroid resistance increased over the study duration in four out of five countries. Insecticide-based vector control may be compromised as a result of ever higher resistance frequencies.

Indicateurs

1 Consultations de la notice

See more details

Détails

Titre: Implications of insecticide resistance for malaria vector control with long-lasting insecticidal nets: trends in pyrethroid resistance during a WHO-coordinated multi-country prospective study
Créateurs - sans rôle: Jackie Cook - Univ London London Sch Hyg & Trop Med, Dept Infect Dis Epidemiol, MRC Trop Epidemiol Grp, Keppel St, London WC1E 7HT, England
Sean Tomlinson - Univ Liverpool Liverpool Sch Trop Med, Dept Vector Biol, Pembroke Pl, Liverpool L3 5QA, Merseyside, England
Immo Kleinschmidt - University of London
Martin James Donnelly - University of Liverpool
Martin Akogbeto - Ctr Rech Entomol Cotonou, Cotonou, Benin
Alioun Adechoubou - Programme Natl Lutte Conte Paludisme PNLP, Ministere Sante, Cotonou, Benin
Achile Massougbodji - Univ Abomey Calavi, Fac Sci Sante, Cotonou, Benin
Mariam Oke-Sopoh - Programme Natl Lutte Conte Paludisme PNLP, Ministere Sante, Cotonou, Benin
Vincent Corbel - Univ Montpellier, CNRS, IRD, MIVEGEC, Montpellier, France
Sylvie Cornelie - Univ Montpellier, CNRS, IRD, MIVEGEC, Montpellier, France
Aurore Ogouyemi-Hounto - Programme Natl Lutte Conte Paludisme PNLP, Ministere Sante, Cotonou, Benin
Josiane Etang - Org Cooperat & Coordinat Lutte Contre Endemies Afr, Yaounde, Cameroon
Herman Parfait Awono-Ambene - Org Cooperat & Coordinat Lutte Contre Endemies Afr, Yaounde, Cameroon
Jude Bigoga - Univ Yaounde I, Natl Reference Unit NRU Vector Control, Biotechnol Ctr, POB 3851, Yaounde, Cameroon
Stanislas Elysee Mandeng - Org Cooperat & Coordinat Lutte Contre Endemies Afr, Yaounde, Cameroon
Boris Njeambosay - Univ Yaounde I, Natl Reference Unit NRU Vector Control, Biotechnol Ctr, POB 3851, Yaounde, Cameroon
Raymond Tabue - Univ Yaounde I, Natl Reference Unit NRU Vector Control, Biotechnol Ctr, POB 3851, Yaounde, Cameroon
Celestin Kouambeng - Minist Publ Hlth, Natl Malaria Control Program, POB 14386, Yaounde, Cameroon
Etienne Fondjo - Minist Publ Hlth, Natl Malaria Control Program, POB 14386, Yaounde, Cameroon
Kamaraju Raghavendra - Natl Inst Malaria Res, Dept Hlth Res, GoI, Sect 8, New Delhi 110077, India
Rajendra M. Bhatt - Natl Inst Malaria Res, Dept Hlth Res, GoI, Sect 8, New Delhi 110077, India
Mehul Kumar Chourasia - Natl Inst Malaria Res, Dept Hlth Res, GoI, Sect 8, New Delhi 110077, India
Dipak K. Swain - Natl Inst Malaria Res, Dept Hlth Res, GoI, Sect 8, New Delhi 110077, India
Sreehari Uragayala - Natl Inst Malaria Res, Dept Hlth Res, GoI, Sect 8, New Delhi 110077, India
Neena Valecha - Natl Inst Malaria Res, Dept Hlth Res, GoI, Sect 8, New Delhi 110077, India
Charles Mbogo - KEMRI Ctr Geog Med Res Coast, POB 230, Kilifi 80108, Kenya
Nabie Bayoh - KEMRI CDC Res & Publ Hlth Collaborat, POB1578, Kisumu 40100, Kenya
Teresa Kinyari - Univ Nairobi, Dept Med Physiol, Coll Hlth Sci, Sch Med, Nairobi, Kenya
Kiambo Njagi - Minist Hlth, Malaria Control Unit, POB 1992, Nairobi 00202, Kenya
Lawrence Muthami - KEMRI Ctr Publ Hlth Res, Nairobi, Kenya
Luna Kamau - KEMRI Ctr Biotechnol & Res Dev, Nairobi, Kenya
Evan Mathenge - KEMRI Eastern & Southern Africa Ctr Int Parasite, Nairobi, Kenya
Eric Ochomo - KEMRI CDC Res & Publ Hlth Collaborat, POB1578, Kisumu 40100, Kenya
Hmooda Toto Kafy - Fed Minist Hlth, Integrated Vector Management Dept, POB 303, Khartoum, Sudan
Bashir Adam Ismail - Khartoum Malaria Free Initiat, Khartoum, Sudan
Elfatih M. Malik - Univ Khartoum, Fac Med, Khartoum, Sudan
Khalid Elmardi - Fed Minist Hlth, Integrated Vector Management Dept, POB 303, Khartoum, Sudan
Jihad Eltaher Sulieman - Sennar Malaria Res & Training Ctr, Sennar, Sudan
Mujahid Abdin - Fed Minist Hlth, Integrated Vector Management Dept, POB 303, Khartoum, Sudan
Krishanthi Subramaniam - Univ Liverpool Liverpool Sch Trop Med, Dept Vector Biol, Pembroke Pl, Liverpool L3 5QA, Merseyside, England
Brent Thomas - Univ Liverpool Liverpool Sch Trop Med, Dept Vector Biol, Pembroke Pl, Liverpool L3 5QA, Merseyside, England
Philippa West - Univ London London Sch Hyg & Trop Med, Dept Infect Dis Epidemiol, MRC Trop Epidemiol Grp, Keppel St, London WC1E 7HT, England
John Bradley - University of London
Tessa Bellamy Knox - WHO, Global Malaria Programme, Ave Appia 20, CH-1211 Geneva, Switzerland
Abraham Peter Mnzava - WHO, Global Malaria Programme, Ave Appia 20, CH-1211 Geneva, Switzerland
Jonathan Lines - London Sch Hyg & Trop Med, Dept Dis Control, Keppel St, London WC1E 7HT, England
Michael Macdonaldand - WHO, Global Malaria Programme, Ave Appia 20, CH-1211 Geneva, Switzerland
Zinga Jose Nkuni - WHO, Global Malaria Programme, Ave Appia 20, CH-1211 Geneva, Switzerland
Kenya Study Team
Détails de publication: Parasites & vectors, Vol.11(1), pp.550-550
Éditeur: Springer Nature
Nombre de pages: 10
Note de subvention: Bill & Melinda Gates Foundation; Bill & Melinda Gates Foundation Grand Challenges Explorations Initiative; CGIAR UK Medical Research Council; UK Research & Innovation (UKRI); Medical Research Council UK (MRC) 1855159 / MRC; UK Research & Innovation (UKRI); Medical Research Council UK (MRC) UK Department for International Development
Identifiants: 99147898609311
Unité académique: Maladies Infectieuses et Vecteurs : Ecologie, Génétique, Evolution et Contrôle - MIVEGEC
Langue: English
Type de ressource: Journal article