Impact of iron deficiency diagnosis using hepcidin mass spectrometry dosage methods on hospital stay and costs after a prolonged ICU stay: Study protocol for a multicentre, randomised, single-blinded medico-economic trial

Sigismond Lasocki; Hervé Puy; Grégoire Mercier; Sylvain Lehmann; Hepcidane Study Group

doi:10.1016/j.accpm.2017.04.009

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Impact of iron deficiency diagnosis using hepcidin mass spectrometry dosage methods on hospital stay and costs after a prolonged ICU stay: Study protocol for a multicentre, randomised, single-blinded medico-economic trial

Journal article

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Impact of iron deficiency diagnosis using hepcidin mass spectrometry dosage methods on hospital stay and costs after a prolonged ICU stay: Study protocol for a multicentre, randomised, single-blinded medico-economic trial

Sigismond Lasocki, Hervé Puy, Grégoire Mercier, Sylvain Lehmann and Hepcidane Study Group

Anaesthesia Critical Care & Pain Medicine, Vol.36(6), pp.391 - 396

12/2017

DOI: https://doi.org/10.1016/j.accpm.2017.04.009

PMID: 28919067

Abstract

Anaemia

Critical care

Hepcidin

Iron deficiency

Length of stay

Medical costs

Iron deficiency (ID) is frequent but difficult to diagnose in critically ill patients. ID may be responsible for prolonged post-ICU hospital stays, since it results in fatigue, muscle weakness and anaemia. Hepcidin, the key iron metabolism hormone, may be a good marker of ID in these patients. The aim of this study is to determine whether using mass spectrometry hepcidin determination to diagnose (and treat) ID after prolonged ICU stays may reduce patients' subsequent hospital stays and costs in comparison with conventional (ferritin) methods.

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Title: Impact of iron deficiency diagnosis using hepcidin mass spectrometry dosage methods on hospital stay and costs after a prolonged ICU stay: Study protocol for a multicentre, randomised, single-blinded medico-economic trial
Creators - without role: Sigismond Lasocki - Université d'Angers
Hervé Puy - Hôpital Louis-Mourier
Grégoire Mercier - Département d'Informatique
Sylvain Lehmann - Université de Montpellier, Cell souches plasticité cellul régénérat tissulaire immuno des maladies inflamm - IRMB
Hepcidane Study Group
Publication Details: Anaesthesia Critical Care & Pain Medicine, Vol.36(6), pp.391 - 396
Identifiers: 9940403409311
Academic Unit: Cell souches plasticité cellul régénérat tissulaire immuno des maladies inflamm - IRMB
Language: English
Resource Type: Journal article
Local Fields: hal-01745569