Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

Catherine M. Phelan; Karoline B. Kuchenbaecker; Jonathan P. Tyrer; Siddhartha P. Kar; Kate Lawrenson; Stacey J. Winham; Joe Dennis; Ailith Pirie; Marjorie J. Riggan; Ganna Chornokur; Madalene A. Earp; Paulo C. Lyra; Janet M. Lee; Simon Coetzee; Jonathan Beesley; Lesley McGuffog; Penny Soucy; Ed Dicks; Andrew Lee; Daniel Barrowdale; Julie Lecarpentier; Goska Leslie; Cora M. Aalfs; Katja K. H. Aben; Marcia Adams; Julian Adlard; Irene L. Andrulis; Hoda Anton-Culver; Natalia Antonenkova; Gerasimos Aravantinos; Norbert Arnold; Banu K. Arun; Brita Arver; Jacopo Azzollini; Judith Balmana; Susana N. Banerjee; Laure Barjhoux; Rosa B. Barkardottir; Yukie Bean; Matthias W. Beckmann; Alicia Beeghly-Fadiel; Javier Benitez; Marina Bermisheva; Marcus Q. Bernardini; Michael J. Birrer; Line Bjorge; Amanda Black; Kenneth Blankstein; Marinus J. Blok; Clara Bodelon; Natalia Bogdanova; Anders Bojesen; Bernardo Bonanni; Ake Borg; Angela R. Bradbury; James D. Brenton; Carole Brewer; Louise Brinton; Per Broberg; Angela Brooks-Wilson; Fiona Bruinsma; Joan Brunet; Bruno Buecher; Ralf Butzow; Saundra S. Buys; Trinidad Caldes; Maria A. Caligo; Ian Campbell; Rikki Cannioto; Michael E. Carney; Terence Cescon; Salina B. Chan; Jenny Chang-Claude; Stephen Chanock; Xiao Qing Chen; Yoke-Eng Chiew; Jocelyne Chiquette; Wendy K. Chung; Kathleen B. M. Claes; Thomas Conner; Linda S. Cook; Jackie Cook; Daniel W. Cramer; Julie M. Cunningham; Aimee A. D'Aloisio; Mary B. Daly; Francesca Damiola; Sakaeva Dina Damirovna; Agnieszka Dansonka-Mieszkowska; Fanny Dao; Rosemarie Davidson; Anna DeFazio; Capucine Delnatte; Kimberly F. Doheny; Orland Diez; Yuan Chun Ding; Jennifer Anne Doherty; Susan M. Domchek; Cecilia M. Dorfling; Thilo Dork; Laure Dossus; Mercedes Duran; Matthias Durst; Bernd Dworniczak; Diana Eccles; Todd Edwards; Ros Eeles; Ursula Eilber; Bent Ejlertsen; Arif B. Ekici; Steve Ellis; Mingajeva Elvira; Kevin H. Eng; Christoph Engel; D. Gareth Evans; Peter A. Fasching; Sarah Ferguson; Sandra Fert Ferrer; James M. Flanagan; Zachary C. Fogarty; Renee T. Fortner; Florentia Fostira; William D. Foulkes; George Fountzilas; Brooke L. Fridley; Tara M. Friebel; Eitan Friedman; Debra Frost; Patricia A. Ganz; Judy Garber; Maria J. Garcia; Vanesa Garcia-Barberan; Andrea Gehrig; Aleksandra Gentry-Maharaj; Anne-Marie Gerdes; Graham G. Giles; Rosalind Glasspool; Gord Glendon; Andrew K. Godwin; David E. Goldgar; Teodora Goranova; Martin Gore; Mark H. Greene; Jacek Gronwald; Stephen Gruber; Eric Hahnen; Christopher A. Haiman; Niclas Hakansson; Ute Hamann; Thomas V. O. Hansen; Patricia A. Harrington; Holly R. Harris; Jan Hauke; Alexander Hein; Alex Henderson; Michelle A. T. Hildebrandt; Peter Hillemanns; Shirley Hodgson; Claus K. Hogdall; Estrid Hogdall; Frans B. L. Hogervorst; Helene Holland; Maartje J. Hooning; Karen Hosking; Ruea-Yea Huang; Peter J. Hulick; Jillian Hung; David J. Hunter; David G. Huntsman; Tomasz Huzarski; Evgeny N. Imyanitov; Claudine Isaacs; Edwin S. Iversen; Louise Izatt; Angel Izquierdo; Anna Jakubowska; Paul James; Ramunas Janavicius; Mats Jernetz; Allan Jensen; Uffe Birk Jensen; Esther M. John; Sharon Johnatty; Michael E. Jones; Paivi Kannisto; Beth Y. Karlan; Anthony Karnezis; Karin Kast; Catherine J. Kennedy; Elza Khusnutdinova; Lambertus A. Kiemeney; Johanna I. Kiiski; Sung-Won Kim; Susanne K. Kjaer; Martin Kobel; Reidun K. Kopperud; Torben A. Kruse; Jolanta Kupryjanczyk; Ava Kwong; Yael Laitman; Diether Lambrechts; Nerea Larranaga; Melissa C. Larson; Conxi Lazaro; Nhu D. Le; Loic Le Marchand; Jong Won Lee; Shashikant B. Lele; Arto Leminen; Dominique Leroux; Jenny Lester; Fabienne Lesueur; Douglas A. Levine; Dong Liang; Clemens Liebrich; Jenna Lilyquist; Loren Lipworth; Jolanta Lissowska; Karen H. Lu; Jan Lubinski; Craig Luccarini; Lene Lundvall; Phuong L. Mai; Gustavo Mendoza-Fandino; Siranoush Manoukian; Leon F. A. G. Massuger; Taymaa May; Sylvie Mazoyer; Jessica N. McAlpine; Valerie McGuire; John R. McLaughlin; Iain McNeish; Hanne Meijers-Heijboer; Alfons Meindl; Usha Menon; Arjen R. Mensenkamp; Melissa A. Merritt; Roger L. Milne; Gillian Mitchell; Francesmary Modugno; Joanna Moes-Sosnowska; Melissa Moffitt; Marco Montagna; Kirsten B. Moysich; Anna Marie Mulligan; Jacob Musinsky; Katherine L. Nathanson; Lotte Nedergaard; Roberta B. Ness; Susan L. Neuhausen; Heli Nevanlinna; Dieter Niederacher; Robert L. Nussbaum; Kunle Odunsi; Edith Olah; Olufunmilayo I. Olopade; Hakan Olsson; Curtis Olswold; David M. O'Malley; Kai-ren Ong; N. Charlotte Onland-Moret; Nicholas Orr; Sandra Orsulic; Ana Osorio; Domenico Palli; Laura Papi; Tjoung-Won Park-Simon; James Paul; Celeste L. Pearce; Inge Sokilde Pedersen; Petra H. M. Peeters; Bernard Peissel; Ana Peixoto; Tanja Pejovic; Liisa M. Pelttari; Jennifer B. Permuth; Paolo Peterlongo; Lidia Pezzani; Georg Pfeiler; Kelly-Anne Phillips; Marion Piedmonte; Malcolm C. Pike; Anna M. Piskorz; Samantha R. Poblete; Timea Pocza; Elizabeth M. Poole; Bruce Poppe; Mary E. Porteous; Fabienne Prieur; Darya Prokofyeva; Elizabeth Pugh; Miquel Angel Pujana; Pascal Pujol; Paolo Radice; Johanna Rantala; Christine Rappaport-Fuerhauser; Gad Rennert; Kerstin Rhiem; Patricia Rice; Andrea Richardson; Mark Robson; Gustavo C. Rodriguez; Cristina Rodriguez-Antona; Jane Romm; Matti A. Rookus; Mary Anne Rossing; Joseph H. Rothstein; Anja Rudolph; Ingo B. Runnebaum; Helga B. Salvesen; Dale P. Sandler; Minouk J. Schoemaker; Leigha Senter; V. Wendy Setiawan; Gianluca Severi; Priyanka Sharma; Tameka Shelford; Nadeem Siddiqui; Lucy E. Side; Weiva Sieh; Christian F. Singer; Hagay Sobol; Honglin Song; Melissa C. Southey; Amanda B. Spurdle; Zsofia Stadler; Doris Steinemann; Dominique Stoppa-Lyonnet; Lara E. Sucheston-Campbell; Grzegorz Sukiennicki; Rebecca Sutphen; Christian Sutter; Anthony J. Swerdlow; Csilla I. Szabo; Lukasz Szafron; Yen Y. Tan; Jack A. Taylor; Muy-Kheng Tea; Manuel R. Teixeira; Soo-Hwang Teo; Kathryn L. Terry; Pamela J. Thompson; Liv Cecilie Vestrheim Thomsen; Darcy L. Thull; Laima Tihomirova; Anna V. Tinker; Marc Tischkowitz; Silvia Tognazzo; Amanda Ewart Toland; Alicia Tone; Britton Trabert; Ruth C. Travis; Antonia Trichopoulou; Nadine Tung; Shelley S. Tworoger; Anne M. Van Altena; David Van den Berg; Annemarie H. van der Hout; Rob B. van der Luijt; Mattias Van Heetvelde; Els Van Nieuwenhuysen; Elizabeth J. Van Rensburg; Adriaan Vanderstichele; Raymonda Varon-Mateeva; Ana Vega; Digna Velez Edwards; Ignace Vergote; Robert A. Vierkant; Joseph Vijai; Athanassios Vratimos; Lisa Walker; Christine Walsh; Dorothea Wand; Shan Wang-Gohrke; Barbara Wappenschmidt; Penelope M. Webb; Clarice R. Weinberg; Jeffrey N. Weitzel; Nicolas Wentzensen; Alice S. Whittemore; Juul T. Wijnen; Lynne R. Wilkens; Alicja Wolk; Michelle Woo; Xifeng Wu; Anna H. Wu; Hannah Yang; Drakoulis Yannoukakos; Argyrios Ziogas; Kristin K. Zorn; Steven A. Narod; Douglas F. Easton; Christopher I. Amos; Joellen M. Schildkraut; Susan J. Ramus; Laura Ottini; Marc T. Goodman; Sue K. Park; Linda E. Kelemen; Harvey A. Risch; Mads Thomassen; Kenneth Offit; Jacques Simard; Rita Katharina Schmutzler; Dennis Hazelett; Alvaro N. Monteiro; Fergus J. Couch; Andrew Berchuck; Georgia Chenevix-Trench; Ellen L. Goode; Thomas A. Sellers; Simon A. Gayther; Antonis C. Antoniou; Paul D. P. Pharoah; KConFab Investigators

doi:10.1038/ng.3826

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Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

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Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

Catherine M. Phelan, Karoline B. Kuchenbaecker, Jonathan P. Tyrer, Siddhartha P. Kar, Kate Lawrenson, Stacey J. Winham, Joe Dennis, Ailith Pirie, Marjorie J. Riggan, Ganna Chornokur, …

Nature genetics, Vol.49(5), pp.680-691

01/05/2017

DOI: https://doi.org/10.1038/ng.3826

PMID: 28346442

Résumé

Genetics & Heredity

Life Sciences & Biomedicine

Science & Technology

To identify common alleles associated with different histotypes of epithelial ovarian cancer (EOC), we pooled data from multiple genome-wide genotyping projects totaling 25,509 EOC cases and 40,941 controls. We identified nine new susceptibility loci for different EOC histotypes: six for serous EOC histotypes (3q28, 4q32.3, 8q21.11, 10q24.33, 18q11.2 and 22q12.1), two for mucinous EOC (3q22.3 and 9q31.1) and one for endometrioid EOC (5q12.3). We then performed meta-analysis on the results for high-grade serous ovarian cancer with the results from analysis of 31,448 BRCA1 and BRCA2 mutation carriers, including 3,887 mutation carriers with EOC. This identified three additional susceptibility loci at 2q13, 8q24.1 and 12q24.31. Integrated analyses of genes and regulatory biofeatures at each locus predicted candidate susceptibility genes, including OBFC1, a new candidate susceptibility gene for low-grade and borderline serous EOC.

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Titre: Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer
Créateurs - sans rôle: Catherine M. Phelan - H Lee Moffitt Canc Ctr & Res Inst, Dept Canc Epidemiol, Tampa, FL USA
Karoline B. Kuchenbaecker - Wellcome Sanger Institute
Jonathan P. Tyrer - Univ Cambridge, Dept Oncol, Strangeways Res Lab, Ctr Canc Genet Epidemiol, Cambridge, England
Siddhartha P. Kar - Univ Cambridge, Dept Oncol, Strangeways Res Lab, Ctr Canc Genet Epidemiol, Cambridge, England
Kate Lawrenson - Cedars Sinai Med Ctr, Samuel Oschin Comprehens Canc Inst, Womens Canc Program, Los Angeles, CA 90048 USA
Stacey J. Winham - Mayo Clin, Div Biomed Stat & Informat, Dept Hlth Sci Res, Rochester, MN USA
Joe Dennis - University of Cambridge
Ailith Pirie - Univ Cambridge, Dept Oncol, Strangeways Res Lab, Ctr Canc Genet Epidemiol, Cambridge, England
Marjorie J. Riggan - Duke Univ, Med Ctr, Dept Obstet & Gynecol, Durham, NC 27710 USA
Ganna Chornokur - H Lee Moffitt Canc Ctr & Res Inst, Dept Canc Epidemiol, Tampa, FL USA
Madalene A. Earp - Mayo Clin, Div Epidemiol, Dept Hlth Sci Res, Rochester, MN USA
Paulo C. Lyra - H Lee Moffitt Canc Ctr & Res Inst, Dept Canc Epidemiol, Tampa, FL USA
Janet M. Lee - Cedars Sinai Med Ctr, Samuel Oschin Comprehens Canc Inst, Ctr Bioinformat & Funct Genom, Los Angeles, CA 90048 USA
Simon Coetzee - Cedars Sinai Med Ctr, Samuel Oschin Comprehens Canc Inst, Ctr Bioinformat & Funct Genom, Los Angeles, CA 90048 USA
Jonathan Beesley - QIMR Berghofer Med Res Inst, Dept Genet & Computat Biol, Brisbane, Qld, Australia
Lesley McGuffog - Univ Cambridge, Dept Publ Hlth & Primary Care, Ctr Canc Genet Epidemiol, Cambridge, England
Penny Soucy - Ctr Hosp Univ Quebec, Genom Ctr, Res Ctr, Quebec City, PQ, Canada
Ed Dicks - Univ Cambridge, Dept Oncol, Strangeways Res Lab, Ctr Canc Genet Epidemiol, Cambridge, England
Andrew Lee - Univ Cambridge, Dept Publ Hlth & Primary Care, Ctr Canc Genet Epidemiol, Cambridge, England
Daniel Barrowdale - Univ Cambridge, Dept Publ Hlth & Primary Care, Ctr Canc Genet Epidemiol, Cambridge, England
Julie Lecarpentier - Univ Cambridge, Dept Publ Hlth & Primary Care, Ctr Canc Genet Epidemiol, Cambridge, England
Goska Leslie - Univ Cambridge, Dept Publ Hlth & Primary Care, Ctr Canc Genet Epidemiol, Cambridge, England
Cora M. Aalfs - Acad Med Ctr, Dept Clin Genet, Amsterdam, Netherlands
Katja K. H. Aben - Radboud Univ Nijmegen, Radboud Inst Hlth Sci, Dept Hlth Evidence, Med Ctr, Nijmegen, Netherlands
Marcia Adams - Johns Hopkins Univ, Sch Med, Inst Med Genet, Ctr Inherited Dis Res, Baltimore, MD USA
Julian Adlard - Chapel Allerton Hosp, Yorkshire Reg Genet Serv, Leeds, W Yorkshire, England
Irene L. Andrulis - Lunenfeld-Tanenbaum Research Institute
Hoda Anton-Culver - Univ Calif Irvine, Sch Med, UCI Ctr Canc Genet Res & Prevent, Genet Epidemiol Res Inst, Irvine, CA 92717 USA
Natalia Antonenkova - NN Alexandrov Natl Canc Ctr Belarus, Minsk, BELARUS
Gerasimos Aravantinos - Agii Anargiri Canc Hosp, Athens, Greece
Norbert Arnold - Christian Albrechts Univ Kiel, Univ Hosp Schleswig Holstein, Dept Gynaecol & Obstet, Campus Kiel, Kiel, Germany
Banu K. Arun - Univ Texas MD Anderson Canc Ctr, Dept Breast Med Oncol, Houston, TX 77030 USA
Brita Arver - Karolinska Univ Hosp, Dept Oncol & Pathol, Stockholm, Sweden
Jacopo Azzollini - Fdn IRCCS Ist Ricovero & Cura Carattere Sci, Ist Nazl Tumori INT, Dept Prevent & Predict Med, Unit Med Genet, Milan, Italy
Judith Balmana - Univ Hosp Vall dHebron, Dept Med Oncol, Barcelona, Spain
Susana N. Banerjee - Royal Marsden Hosp, Gynaecol Unit, London, England
Laure Barjhoux - Ctr Leon Berard, Batiment Cheney D, Lyon, France
Rosa B. Barkardottir - Landspitali, Dept Pathol, Lab Cell Biol, Reykjavik, Iceland
Yukie Bean - Oregon Hlth & Sci Univ, Dept Gynecol Oncol, Portland, OR 97201 USA
Matthias W. Beckmann - Friedrich Alexander Univ Erlangen Nuremberg, Comprehens Canc Ctr Erlangen Nuremberg, Univ Hosp Erlangen, Dept Gynecol & Obstet, Erlangen, Germany
Alicia Beeghly-Fadiel - Vanderbilt Univ, Sch Med, Dept Med, Div Epidemiol, Nashville, TN 37212 USA
Javier Benitez - Spanish Natl Canc Ctr CNIO, Human Genet Grp, Madrid, Spain
Marina Bermisheva - Russian Acad Sci, Ufa Sci Ctr, Inst Biochem & Genet, Ufa, Russia
Marcus Q. Bernardini - Princess Margaret Hosp, Univ Hlth Network, Div Gynecol Oncol, Toronto, ON, Canada
Michael J. Birrer - Massachusetts Gen Hosp, Dept Med, Boston, MA 02114 USA
Line Bjorge - Haukeland Hosp, Dept Gynecol & Obstet, Bergen, Norway
Amanda Black - NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA
Kenneth Blankstein - Clin Canc Genet City Hope, Clin Canc Genet Community Res Network, Duarte, CA USA
Marinus J. Blok - Maastricht University
Clara Bodelon - NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA
Natalia Bogdanova - Hannover Med Sch, Radiat Oncol Res Unit, Hannover, Germany
Anders Bojesen - Vejle Hosp, Dept Clin Genet, Vejle, Denmark
Bernardo Bonanni - Ist Europeo Oncol IEO, Div Canc Prevent & Genet, Milan, Italy
Ake Borg - Lund University
Angela R. Bradbury - Univ Penn, Dept Med, Abramson Canc Ctr, Perelman Sch Med, Philadelphia, PA 19104 USA
James D. Brenton - Univ Cambridge, Canc Res UK CRUK Cambridge Inst, Cambridge, England
Carole Brewer - Royal Devon University Healthcare NHS Foundation Trust
Louise Brinton - NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA
Per Broberg - Lund Univ, Dept Canc Epidemiol, Univ Hosp, Lund, Sweden
Angela Brooks-Wilson - BC Canc Agcy, Canadas Michael Smith Genome Sci Ctr, Vancouver, BC, Canada
Fiona Bruinsma - Canc Council Victoria, Canc Epidemiol Ctr, Melbourne, Vic, Australia
Joan Brunet - Catalan Inst Oncol, IDIBGI Inst Invest Biomed Girona, Hereditary Canc Program, Genet Counseling Unit, Girona, Spain
Bruno Buecher - Inst Curie, Serv Genet Oncol, Paris, France
Ralf Butzow - Univ Helsinki, Dept Pathol, Helsinki, Finland
Saundra S. Buys - Huntsman Canc Inst, Dept Med, Salt Lake City, UT USA
Trinidad Caldes - Hosp Clin San Carlos, Inst Invest Sanitaria, IdISSC, Mol Oncol Lab, Madrid, Spain
Maria A. Caligo - University of Pisa
Ian Campbell - Peter MacCallum Canc Ctr, Div Res, Canc Genet Lab, Melbourne, Vic, Australia
Rikki Cannioto - Roswell Pk Canc Inst, Div Canc Prevent & Populat Sci, Canc Pathol & Prevent, Buffalo, NY 14263 USA
Michael E. Carney - Univ Hawaii, John A Burns Sch Med, Dept Obstet & Gynecol, Honolulu, HI 96822 USA
Terence Cescon - Clin Canc Genet City Hope, Clin Canc Genet Community Res Network, Duarte, CA USA
Salina B. Chan - Univ Calif San Francisco, Canc Risk Program, San Francisco, CA 94143 USA
Jenny Chang-Claude - German Canc Res Ctr, Div Canc Epidemiol, Heidelberg, Germany
Stephen Chanock - NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA
Xiao Qing Chen - QIMR Berghofer Med Res Inst, Dept Genet & Computat Biol, Brisbane, Qld, Australia
Yoke-Eng Chiew - Univ Sydney, Westmead Inst Med Res, Ctr Canc Res, Sydney, NSW, Australia
Jocelyne Chiquette - Univ Quebec, Ctr Hosp, Ctr Rech FRSQ, Unite Rech Sante Populat,Ctr Malad Sein Deschenes, Quebec City, PQ, Canada
Wendy K. Chung - Columbia Univ, Dept Pediat, New York, NY 10027 USA
Kathleen B. M. Claes - Univ Ghent, Ctr Med Genet, Ghent, Belgium
Thomas Conner - Huntsman Canc Inst, Dept Med, Salt Lake City, UT USA
Linda S. Cook - Univ New Mexico, Dept Internal Med, Div Epidemiol Biostatist & Preventat Med, Albuquerque, NM 87131 USA
Jackie Cook - Sheffield Childrens Hosp, Sheffield Clin Genet Serv, Sheffield, S Yorkshire, England
Daniel W. Cramer - Brigham & Womens Hosp, Obstet & Gynecol Epidemiol Ctr, 75 Francis St, Boston, MA 02115 USA
Julie M. Cunningham - Mayo Clin, Dept Lab Med & Pathol, Div Expt Pathol, Rochester, MN USA
Aimee A. D'Aloisio - Social & Sci Syst Inc, Durham, NC USA
Mary B. Daly - Fox Chase Canc Ctr, Dept Clin Genet, 7701 Burholme Ave, Philadelphia, PA 19111 USA
Francesca Damiola - Ctr Leon Berard, Batiment Cheney D, Lyon, France
Sakaeva Dina Damirovna - Bashkir State Univ, Dept Genet & Fundamental Med, Ufa, Russia
Agnieszka Dansonka-Mieszkowska - Maria Sklodowska Curie Mem Canc Ctr, Dept Pathol & Lab Diagnost, Warsaw, Poland
Fanny Dao - Mem Sloan Kettering Canc Ctr, Dept Surg, Gynecol Serv, 1275 York Ave, New York, NY 10021 USA
Rosemarie Davidson - University of Glasgow
Anna DeFazio - Univ Sydney, Westmead Inst Med Res, Ctr Canc Res, Sydney, NSW, Australia
Capucine Delnatte - Université de Nantes
Kimberly F. Doheny - Johns Hopkins Univ, Sch Med, Inst Med Genet, Ctr Inherited Dis Res, Baltimore, MD USA
Orland Diez - Vall dHebron Inst Oncol, Oncogenet Grp, Barcelona, Spain
Yuan Chun Ding - Beckman Research Institute
Jennifer Anne Doherty - Geisel Sch Med Dartmouth, Dept Epidemiol, Hanover, NH USA
Susan M. Domchek - Univ Penn, Dept Med, Abramson Canc Ctr, Perelman Sch Med, Philadelphia, PA 19104 USA
Cecilia M. Dorfling - University of Pretoria
Thilo Dork - Hannover Med Sch, Gynaecol Res Unit, Hannover, Germany
Laure Dossus - Int Agcy Res Canc IARC WHO, Nutr & Metab Sect, Lyon, France
Mercedes Duran - Univ Valladolid IBGM UVA, Inst Biol & Mol Genet, Valladolid, Spain
Matthias Durst - Friedrich Schiller Univ, Jena Univ Hosp, Dept Gynecol, Jena, Germany
Bernd Dworniczak - Inst Human Genet, Munster, Germany
Diana Eccles - University of Southampton
Todd Edwards - Vanderbilt Univ, Sch Med, Dept Med, Div Epidemiol, Nashville, TN 37212 USA
Ros Eeles - Inst Canc Res, Oncogenet Team, Sutton, Surrey, England
Ursula Eilber - German Canc Res Ctr, Div Canc Epidemiol, Heidelberg, Germany
Bent Ejlertsen - Copenhagen Univ Hosp, Rigshosp, Dept Oncol, Copenhagen, Denmark
Arif B. Ekici - Friedrich Alexander Univ Erlangen Nuremberg, Inst Human Genet, Erlangen, Germany
Steve Ellis - Univ Cambridge, Dept Publ Hlth & Primary Care, Ctr Canc Genet Epidemiol, Cambridge, England
Mingajeva Elvira - Bashkir State Univ, Dept Genet & Fundamental Med, Ufa, Russia
Kevin H. Eng - Roswell Pk Inst, Dept Biostat & Bioinformat, Buffalo, NY USA
Christoph Engel - Univ Leipzig, Inst Med Informat Stat & Epidemiol, Leipzig, Germany
D. Gareth Evans - Univ Manchester, Genom Med, Manchester Acad Hlth Sci Ctr, Cent Manchester Univ Hosp NHS Fdn Trust, Manchester, Lancs, England
Peter A. Fasching - Friedrich-Alexander-Universität Erlangen-Nürnberg
Sarah Ferguson - Princess Margaret Hosp, Univ Hlth Network, Div Gynecol Oncol, Toronto, ON, Canada
Sandra Fert Ferrer - Hotel Dieu Ctr Hosp, Lab Genet Chromosom, Chambery, France
James M. Flanagan - Imperial Coll London, Dept Surg & Canc, London, England
Zachary C. Fogarty - Mayo Clin, Div Biomed Stat & Informat, Dept Hlth Sci Res, Rochester, MN USA
Renee T. Fortner - German Canc Res Ctr, Div Canc Epidemiol, Heidelberg, Germany
Florentia Fostira - National Centre of Scientific Research "Demokritos"
William D. Foulkes - McGill Univ, Dept Human Genet, Program Canc Genet, Montreal, PQ, Canada
George Fountzilas - Aristotle Univ Thessaloniki, Sch Med, Papageorgiou Hosp, Dept Med Oncol, Thessaloniki, Greece
Brooke L. Fridley - Univ Kansas, Med Ctr, Biostat & Informat Shared Resource, Kansas City, KS 66103 USA
Tara M. Friebel - Harvard TH Chan Sch Publ Hlth, Boston, MA USA
Eitan Friedman - Chaim Sheba Med Ctr, Inst Human Genet, Susanne Levy Gertner Oncogenet Unit, Ramat Gan, Israel
Debra Frost - Univ Cambridge, Dept Publ Hlth & Primary Care, Ctr Canc Genet Epidemiol, Cambridge, England
Patricia A. Ganz - Univ Calif Los Angeles, Jonsson Comprehens Canc Ctr, Sch Med, Div Canc Prevent & Control Res, Los Angeles, CA 90024 USA
Judy Garber - Dana Farber Canc Inst, Canc Risk & Prevent Clin, Boston, MA 02115 USA
Maria J. Garcia - Spanish Natl Canc Ctr CNIO, Human Genet Grp, Madrid, Spain
Vanesa Garcia-Barberan - Hosp Clin San Carlos, Inst Invest Sanitaria, IdISSC, Mol Oncol Lab, Madrid, Spain
Andrea Gehrig - University of Würzburg
Aleksandra Gentry-Maharaj - UCL, Inst Womens Hlth, Womens Canc, London, England
Anne-Marie Gerdes - Copenhagen Univ Hosp, Rigshosp, Dept Clin Genet, Copenhagen, Denmark
Graham G. Giles - Canc Council Victoria, Canc Epidemiol Ctr, Melbourne, Vic, Australia
Rosalind Glasspool - Beatson West Scotland Canc Ctr, Glasgow, Lanark, Scotland
Gord Glendon - Lunenfeld-Tanenbaum Research Institute
Andrew K. Godwin - University of Kansas
David E. Goldgar - University of Utah
Teodora Goranova - Univ Cambridge, Canc Res UK CRUK Cambridge Inst, Cambridge, England
Martin Gore - Royal Marsden Hosp, Dept Med, London, England
Mark H. Greene - NCI, Clin Genet Branch, Div Canc Epidemiol & Genet, US Natl Inst Hlth, Bethesda, MD 20892 USA
Jacek Gronwald - University of Szczecin
Stephen Gruber - Univ Southern Calif, Keck Sch Med, Los Angeles, CA USA
Eric Hahnen - Univ Hosp Cologne, Ctr Integrated Oncol, Ctr Familial Breast & Ovarian Canc, Cologne, Germany
Christopher A. Haiman - Univ Southern Calif, Keck Sch Med, Dept Prevent Med, Norris Comprehens Canc Ctr, Los Angeles, CA USA
Niclas Hakansson - Karolinska Inst, Dept Environm Med, Div Nutr Epidemiol, Stockholm, Sweden
Ute Hamann - Deutsch Krebsforschungszentrum DKFZ, Mol Genet Breast Canc, Heidelberg, Germany
Thomas V. O. Hansen - Copenhagen Univ Hosp, Ctr Genom Med, Rigshosp, Copenhagen, Denmark
Patricia A. Harrington - University of Cambridge
Holly R. Harris - Karolinska Inst, Dept Environm Med, Div Nutr Epidemiol, Stockholm, Sweden
Jan Hauke - Univ Hosp Cologne, Ctr Integrated Oncol, Ctr Familial Breast & Ovarian Canc, Cologne, Germany
Alexander Hein - Friedrich Alexander Univ Erlangen Nuremberg, Comprehens Canc Ctr Erlangen Nuremberg, Univ Hosp Erlangen, Dept Gynecol & Obstet, Erlangen, Germany
Alex Henderson - Newcastle Upon Tyne Hosp NHS Trust, Ctr Life, Inst Genet Med, Newcastle Upon Tyne, Tyne & Wear, England
Michelle A. T. Hildebrandt - Univ Texas MD Anderson Canc Ctr, Dept Epidemiol, Houston, TX 77030 USA
Peter Hillemanns - Hannover Med Sch, Clin Obstet, Hannover, Germany
Shirley Hodgson - University of London
Claus K. Hogdall - Univ Copenhagen, Rigshosp, Dept Gynecol, Copenhagen, Denmark
Estrid Hogdall - Danish Canc Soc, Res Ctr, Dept Virus Lifestyle & Genes, Copenhagen, Denmark
Frans B. L. Hogervorst - Netherlands Canc Inst, Family Canc Clin, Amsterdam, Netherlands
Helene Holland - QIMR Berghofer Med Res Inst, Dept Genet & Computat Biol, Brisbane, Qld, Australia
Maartje J. Hooning - Erasmus Univ, Med Ctr, Family Canc Clin, Dept Med Oncol, Rotterdam, Netherlands
Karen Hosking - Univ Cambridge, Dept Oncol, Strangeways Res Lab, Ctr Canc Genet Epidemiol, Cambridge, England
Ruea-Yea Huang - Roswell Pk Canc Inst, Ctr Immunotherapy, Buffalo, NY 14263 USA
Peter J. Hulick - Univ Chicago, Pritzker Sch Med, NorthShore Univ HealthSyst, Ctr Med Genet, Evanston, IL USA
Jillian Hung - Univ Sydney, Westmead Inst Med Res, Ctr Canc Res, Sydney, NSW, Australia
David J. Hunter
David G. Huntsman - Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Program Genet Epidemiol & Stat Genet, Boston, MA USA
Tomasz Huzarski - University of Szczecin
Evgeny N. Imyanitov - NN Petrov Inst Oncol, St Petersburg, Russia
Claudine Isaacs - Georgetown University
Edwin S. Iversen - Duke Univ, Dept Stat Sci, Durham, NC USA
Louise Izatt - Guys & St Thomas NHS Fdn Trust, Clin Genet, London, England
Angel Izquierdo - Catalan Inst Oncol, IDIBGI Inst Invest Biomed Girona, Hereditary Canc Program, Genet Counseling Unit, Girona, Spain
Anna Jakubowska - University of Szczecin
Paul James - Peter MacCallum Canc Ctr, Familial Canc Ctr, Melbourne, Vic, Australia
Ramunas Janavicius - Vilnius University
Mats Jernetz - Univ Lund Hosp, Dept Obstet & Gynecol, Lund, Sweden
Allan Jensen - Danish Canc Soc, Res Ctr, Dept Virus Lifestyle & Genes, Copenhagen, Denmark
Uffe Birk Jensen - Aarhus Univ Hosp, Dept Clin Genet, Aarhus, Denmark
Esther M. John - Canc Prevent Inst Calif, Dept Epidemiol, Fremont, CA USA
Sharon Johnatty - QIMR Berghofer Med Res Inst, Dept Genet & Computat Biol, Brisbane, Qld, Australia
Michael E. Jones - Inst Canc Res, Div Genet & Epidemiol, London, England
Paivi Kannisto - Univ Lund Hosp, Dept Obstet & Gynecol, Lund, Sweden
Beth Y. Karlan - College Station Medical Center
Anthony Karnezis - Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Program Genet Epidemiol & Stat Genet, Boston, MA USA
Karin Kast - Tech Univ Dresden, Univ Hosp Carl Gustav Carus, Dept Gynaecol & Obstet, Dresden, Germany
Catherine J. Kennedy - Univ Sydney, Westmead Inst Med Res, Ctr Canc Res, Sydney, NSW, Australia
Elza Khusnutdinova - Russian Acad Sci, Ufa Sci Ctr, Inst Biochem & Genet, Ufa, Russia
Lambertus A. Kiemeney - Radboud Univ Nijmegen, Radboud Inst Hlth Sci, Dept Hlth Evidence, Med Ctr, Nijmegen, Netherlands
Johanna I. Kiiski - Univ Helsinki, Dept Obstet & Gynecol, Helsinki, Finland
Sung-Won Kim - Daerim St Marys Hosp, Breast Care Ctr, Dept Surg, Seoul, South Korea
Susanne K. Kjaer - Univ Copenhagen, Rigshosp, Dept Gynecol, Copenhagen, Denmark
Martin Kobel - Univ Calgary, Dept Pathol, Calgary, AB, Canada
Reidun K. Kopperud - Haukeland Hosp, Dept Gynecol & Obstet, Bergen, Norway
Torben A. Kruse - Odense Univ Hosp, Dept Clin Genet, Odense, Denmark
Jolanta Kupryjanczyk - Maria Sklodowska Curie Mem Canc Ctr, Dept Pathol & Lab Diagnost, Warsaw, Poland
Ava Kwong - Univ Hawaii, John A Burns Sch Med, Dept Obstet & Gynecol, Honolulu, HI 96822 USA
Yael Laitman - Chaim Sheba Med Ctr, Inst Human Genet, Susanne Levy Gertner Oncogenet Unit, Ramat Gan, Israel
Diether Lambrechts - Univ Calif San Francisco, Canc Risk Program, San Francisco, CA 94143 USA
Nerea Larranaga - Reg Govt Basque Country, Publ Hlth Div Gipuzkoa, Donostia San Sebastian, Spain
Melissa C. Larson - Mayo Clin, Div Biomed Stat & Informat, Dept Hlth Sci Res, Rochester, MN USA
Conxi Lazaro - IDIBELL Catalan Inst Oncol, Hereditary Canc Program, Mol Diagnost Unit, Barcelona, Spain
Nhu D. Le - BC Canc Agcy, Canc Control Res, Vancouver, BC, Canada
Loic Le Marchand - Univ Hawaii, Ctr Canc, Canc Epidemiol Program, Honolulu, HI 96822 USA
Jong Won Lee - Ulsan Coll Med, Dept Surg, Seoul, South Korea
Shashikant B. Lele - Roswell Pk Canc Inst, Dept Gynecol Oncol, Buffalo, NY 14263 USA
Arto Leminen - Univ Helsinki, Dept Obstet & Gynecol, Helsinki, Finland
Dominique Leroux - Ctr Hosp Univ Grenoble, Dept Genet, Grenoble, France
Jenny Lester - College Station Medical Center
Fabienne Lesueur - PSL Res Unviers, Inst Curie, Paris, France
Douglas A. Levine - Mem Sloan Kettering Canc Ctr, Dept Surg, Gynecol Serv, 1275 York Ave, New York, NY 10021 USA
Dong Liang - Texas Southern Univ, Coll Pharm & Hlth Sci, Houston, TX 77004 USA
Clemens Liebrich - Canc Ctr Wolfsburg, Clin Gynaecol, Wolfsburg, Germany
Jenna Lilyquist - Mayo Clin, Div Epidemiol, Dept Hlth Sci Res, Rochester, MN USA
Loren Lipworth - Vanderbilt Univ, Sch Med, Dept Med, Div Epidemiol, Nashville, TN 37212 USA
Jolanta Lissowska - Maria Sklodowska Curie Mem Canc Ctr, Dept Canc Epidemiol & Prevent, Warsaw, Poland
Karen H. Lu - Univ Texas MD Anderson Canc Ctr, Dept Gynecol Oncol, Houston, TX 77030 USA
Jan Lubinski - University of Szczecin
Craig Luccarini - Univ Cambridge, Dept Oncol, Strangeways Res Lab, Ctr Canc Genet Epidemiol, Cambridge, England
Lene Lundvall - University of Copenhagen
Phuong L. Mai - NCI, Clin Genet Branch, Div Canc Epidemiol & Genet, US Natl Inst Hlth, Bethesda, MD 20892 USA
Gustavo Mendoza-Fandino - H Lee Moffitt Canc Ctr & Res Inst, Dept Canc Epidemiol, Tampa, FL USA
Siranoush Manoukian - Fdn IRCCS Ist Ricovero & Cura Carattere Sci, Ist Nazl Tumori INT, Dept Prevent & Predict Med, Unit Med Genet, Milan, Italy
Leon F. A. G. Massuger - Radboud Univ Nijmegen, Radboud Inst Hlth Sci, Dept Hlth Evidence, Med Ctr, Nijmegen, Netherlands
Taymaa May - Princess Margaret Hosp, Univ Hlth Network, Div Gynecol Oncol, Toronto, ON, Canada
Sylvie Mazoyer - Univ Lyon 1, INSERM, U1052, CNRS,UMR 5286,Ctr Rech Cancerol Lyon,Ctr Leon Ber, Lyon, France
Jessica N. McAlpine - Vancouver Gen Hosp, Ovarian Canc Res OVCARE Program, Gynecol Tissue Bank, Vancouver, BC, Canada
Valerie McGuire - Stanford Univ, Sch Med, Dept Hlth Res & Policy Epidemiol, Stanford, CA 94305 USA
John R. McLaughlin - Publ Hlth Ontario, Toronto, ON, Canada
Iain McNeish - Univ Glasgow, Wolfson Wohl Canc Res Ctr, Beatson Inst Canc Res, Inst Canc Sci, Glasgow, Lanark, Scotland
Hanne Meijers-Heijboer - University of Amsterdam
Alfons Meindl - Ludwig-Maximilians-Universität München
Usha Menon - UCL, Inst Womens Hlth, Womens Canc, London, England
Arjen R. Mensenkamp - Radboud University Nijmegen
Melissa A. Merritt - Imperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostat, London, England
Roger L. Milne - Canc Council Victoria, Canc Epidemiol Ctr, Melbourne, Vic, Australia
Gillian Mitchell - Peter MacCallum Canc Ctr, Familial Canc Ctr, Melbourne, Vic, Australia
Francesmary Modugno - Univ Pittsburgh, Sch Med, Dept Obstet Gynecol & Reprod Sci, Div Gynecol Oncol, Pittsburgh, PA USA
Joanna Moes-Sosnowska - Maria Sklodowska Curie Mem Canc Ctr, Dept Pathol & Lab Diagnost, Warsaw, Poland
Melissa Moffitt - Oregon Hlth & Sci Univ, Knight Canc Inst, Portland, OR 97201 USA
Marco Montagna - Veneto Inst Oncol IOV IRCCS, Immunol & Mol Oncol Unit, Padua, Italy
Kirsten B. Moysich - Roswell Pk Canc Inst, Div Canc Prevent & Populat Sci, Canc Pathol & Prevent, Buffalo, NY 14263 USA
Anna Marie Mulligan - University of Toronto
Jacob Musinsky - Mem Sloan Kettering Canc Ctr, Dept Med, Clin Genet Res Lab, 1275 York Ave, New York, NY 10021 USA
Katherine L. Nathanson - Univ Penn, Dept Med, Abramson Canc Ctr, Perelman Sch Med, Philadelphia, PA 19104 USA
Lotte Nedergaard - Univ Copenhagen, Dept Pathol, Rigshosp, Copenhagen, Denmark
Roberta B. Ness - Univ Texas Houston, Sch Publ Hlth, Houston, TX USA
Susan L. Neuhausen - Beckman Research Institute
Heli Nevanlinna - Univ Helsinki, Dept Obstet & Gynecol, Helsinki, Finland
Dieter Niederacher - Heinrich Heine University Düsseldorf
Robert L. Nussbaum - Invitae
Kunle Odunsi - Roswell Pk Canc Inst, Dept Gynecol Oncol, Buffalo, NY 14263 USA
Edith Olah - Natl Inst Oncol, Dept Mol Genet, Budapest, Hungary
Olufunmilayo I. Olopade - University of Chicago
Hakan Olsson - Lund University
Curtis Olswold - Mayo Clin, Div Epidemiol, Dept Hlth Sci Res, Rochester, MN USA
David M. O'Malley - Ohio State Univ, Dept Obstet & Gynecol, Columbus, OH 43210 USA
Kai-ren Ong - Birmingham Womens Hosp Healthcare NHS Trust, West Midlands Reg Genet Serv, Birmingham, W Midlands, England
N. Charlotte Onland-Moret - Univ Med Ctr Utrecht, Julius Ctr Hlth Sci & Primary Care, Utrecht, Netherlands
Nicholas Orr - Inst Canc Res, Breast Canc Now Toby Robins Res Ctr, London, England
Sandra Orsulic - College Station Medical Center
Ana Osorio - Spanish Natl Canc Ctr CNIO, Human Genet Grp, Madrid, Spain
Domenico Palli - Canc Res & Prevent Inst ISPO, Mol & Nutr Epidemiol Unit, Florence, Italy
Laura Papi - University of Florence
Tjoung-Won Park-Simon - Hannover Med Sch, Clin Obstet, Hannover, Germany
James Paul - Univ Glasgow, Inst Canc Sci, Canc Res UK Clin Trials Unit, Glasgow, Lanark, Scotland
Celeste L. Pearce - Univ Southern Calif, Keck Sch Med, Dept Prevent Med, Norris Comprehens Canc Ctr, Los Angeles, CA USA
Inge Sokilde Pedersen - Aalborg Univ Hosp, Clin Biochem, Sect Mol Diagnost, Aalborg, Denmark
Petra H. M. Peeters - Univ Med Ctr Utrecht, Julius Ctr Hlth Sci & Primary Care, Utrecht, Netherlands
Bernard Peissel - Fdn IRCCS Ist Ricovero & Cura Carattere Sci, Ist Nazl Tumori INT, Dept Prevent & Predict Med, Unit Med Genet, Milan, Italy
Ana Peixoto - Portuguese Oncol Inst, Dept Genet, Porto, Portugal
Tanja Pejovic - Oregon Hlth & Sci Univ, Knight Canc Inst, Portland, OR 97201 USA
Liisa M. Pelttari - Univ Helsinki, Dept Obstet & Gynecol, Helsinki, Finland
Jennifer B. Permuth - H Lee Moffitt Canc Ctr & Res Inst, Dept Canc Epidemiol, Tampa, FL USA
Paolo Peterlongo - FIRC Italian Fdn Canc Res, IFOM, Inst Mol Oncol, Milan, Italy
Lidia Pezzani - Fdn IRCCS Ist Ricovero & Cura Carattere Sci, Ist Nazl Tumori INT, Dept Prevent & Predict Med, Unit Med Genet, Milan, Italy
Georg Pfeiler - University of Vienna
Kelly-Anne Phillips - Univ Melbourne, Sch Populat & Global Hlth, Ctr Epidemiol & Biostat, Melbourne, Vic, Australia
Marion Piedmonte - Roswell Pk Canc Inst, NRG Oncol Stat & Data Management Ctr, Buffalo, NY 14263 USA
Malcolm C. Pike - Univ Southern Calif, Keck Sch Med, Dept Prevent Med, Norris Comprehens Canc Ctr, Los Angeles, CA USA
Anna M. Piskorz - Univ Cambridge, Canc Res UK CRUK Cambridge Inst, Cambridge, England
Samantha R. Poblete - Roswell Pk Canc Inst, Dept Gynecol Oncol, Buffalo, NY 14263 USA
Timea Pocza - Natl Inst Oncol, Dept Mol Genet, Budapest, Hungary
Elizabeth M. Poole - Brigham & Womens Hosp, Channing Div Network Med, 75 Francis St, Boston, MA 02115 USA
Bruce Poppe - Univ Ghent, Ctr Med Genet, Ghent, Belgium
Mary E. Porteous - Western Gen Hosp, South East Scotland Reg Genet Serv, Edinburgh, Midlothian, Scotland
Fabienne Prieur - Ctr Hosp Univ St Etienne, Serv Genet Clin Chromosom & Mol, St Etienne, France
Darya Prokofyeva - Bashkir State Univ, Dept Genet & Fundamental Med, Ufa, Russia
Elizabeth Pugh - Johns Hopkins Univ, Sch Med, Inst Med Genet, Ctr Inherited Dis Res, Baltimore, MD USA
Miquel Angel Pujana - IDIBELL Bellvitge Biomed Res Inst, Catalan Inst Oncol, Translat Res Lab, Barcelona, Spain
Pascal Pujol - Ctr Hosp Univ Arnaud Villeneuve, Unite Oncogenet, Montpellier, France
Paolo Radice - Fdn IRCCS Ist Ricovero & Cura Carattere Sci, Ist Nazl Tumori INT, Dept Prevent & Predict Med, Unit Mol Bases Genet Risk & Genet Testing, Milan, Italy
Johanna Rantala - Karolinska Univ Hosp, Dept Clin Genet, Stockholm, Sweden
Christine Rappaport-Fuerhauser - Med Univ Vienna, Dept Obstet & Gynecol, Vienna, Austria
Gad Rennert - Clalit Natl Israeli Canc Control Ctr, Haifa, Israel
Kerstin Rhiem - Univ Hosp Cologne, Ctr Integrated Oncol, Ctr Familial Breast & Ovarian Canc, Cologne, Germany
Patricia Rice - Clin Canc Genet City Hope, Clin Canc Genet Community Res Network, Duarte, CA USA
Andrea Richardson - Brigham and Women's Hospital
Mark Robson - Mem Sloan Kettering Canc Ctr, Dept Med, Clin Genet Serv, 1275 York Ave, New York, NY 10021 USA
Gustavo C. Rodriguez - University of Chicago
Cristina Rodriguez-Antona - Biomed Network Rare Dis CIBERER, Madrid, Spain
Jane Romm - Johns Hopkins Univ, Sch Med, Inst Med Genet, Ctr Inherited Dis Res, Baltimore, MD USA
Matti A. Rookus - Netherlands Canc Inst, Dept Epidemiol, Amsterdam, Netherlands
Mary Anne Rossing - Fred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, Program Epidemiol, 1124 Columbia St, Seattle, WA 98104 USA
Joseph H. Rothstein - Stanford Univ, Sch Med, Dept Hlth Res & Policy Epidemiol, Stanford, CA 94305 USA
Anja Rudolph - German Canc Res Ctr, Div Canc Epidemiol, Heidelberg, Germany
Ingo B. Runnebaum - Friedrich Schiller Univ, Jena Univ Hosp, Dept Gynecol, Jena, Germany
Helga B. Salvesen - Haukeland Hosp, Dept Gynecol & Obstet, Bergen, Norway
Dale P. Sandler - NIEHS, Epidemiol Branch, Div Intramural Res, US Natl Inst Hlth, POB 12233, Res Triangle Pk, NC 27709 USA
Minouk J. Schoemaker - Inst Canc Res, Div Genet & Epidemiol, London, England
Leigha Senter - The Ohio State University
V. Wendy Setiawan - Univ Southern Calif, Keck Sch Med, Dept Prevent Med, Norris Comprehens Canc Ctr, Los Angeles, CA USA
Gianluca Severi - Univ Paris Sud, Fac Med, Villejuif, France
Priyanka Sharma - Univ Kansas, Med Ctr, Dept Hematol & Oncol, Kansas City, KS 66103 USA
Tameka Shelford - Johns Hopkins Univ, Sch Med, Inst Med Genet, Ctr Inherited Dis Res, Baltimore, MD USA
Nadeem Siddiqui - Glasgow Royal Infirm, Dept Gynaecol Oncol, Glasgow, Lanark, Scotland
Lucy E. Side - Great Ormond St Hosp Sick Children, North East Thames Reg Genet Serv, London, England
Weiva Sieh - Stanford Univ, Sch Med, Dept Hlth Res & Policy Epidemiol, Stanford, CA 94305 USA
Christian F. Singer - University of Vienna
Hagay Sobol - Inst Paoli Calmettes, Dept Oncol Genet, Marseille, France
Honglin Song - Univ Cambridge, Dept Oncol, Strangeways Res Lab, Ctr Canc Genet Epidemiol, Cambridge, England
Melissa C. Southey - Univ Melbourne, Dept Pathol, Genet Epidemiol Lab, Parkville, Vic, Australia
Amanda B. Spurdle - QIMR Berghofer Med Res Inst, Dept Genet & Computat Biol, Brisbane, Qld, Australia
Zsofia Stadler - Mem Sloan Kettering Canc Ctr, Dept Med, Clin Genet Serv, 1275 York Ave, New York, NY 10021 USA
Doris Steinemann - Hannover Med Sch, Inst Human Genet, Hannover, Germany
Dominique Stoppa-Lyonnet - Inst Curie, Serv Genet Oncol, Paris, France
Lara E. Sucheston-Campbell - Roswell Pk Canc Inst, Dept Canc Prevent & Control, Buffalo, NY 14263 USA
Grzegorz Sukiennicki - University of Szczecin
Rebecca Sutphen - Univ S Florida, Coll Med, Epidemiol Ctr, Tampa, FL USA
Christian Sutter - Univ Heidelberg Hosp, Dept Human Genet, Inst Human Genet, Heidelberg, Germany
Anthony J. Swerdlow - Inst Canc Res, Div Genet & Epidemiol, London, England
Csilla I. Szabo - NHGRI, US Natl Inst Hlth, Bethesda, MD 20892 USA
Lukasz Szafron - Maria Sklodowska Curie Mem Canc Ctr, Dept Pathol & Lab Diagnost, Warsaw, Poland
Yen Y. Tan - University of Vienna
Jack A. Taylor - NIEHS, Epidemiol Branch, Div Intramural Res, US Natl Inst Hlth, POB 12233, Res Triangle Pk, NC 27709 USA
Muy-Kheng Tea - Med Univ Vienna, Dept Obstet & Gynecol, Vienna, Austria
Manuel R. Teixeira - Portuguese Oncol Inst, Dept Genet, Porto, Portugal
Soo-Hwang Teo - Canc Res Initiat Fdn, Sime Darby Med Ctr, Subang Jaya, Malaysia
Kathryn L. Terry - Brigham & Womens Hosp, Obstet & Gynecol Epidemiol Ctr, 75 Francis St, Boston, MA 02115 USA
Pamela J. Thompson - Cedars Sinai Med Ctr, Samuel Oschin Comprehens Canc Inst, Canc Prevent & Control, Los Angeles, CA 90048 USA
Liv Cecilie Vestrheim Thomsen - Haukeland Hosp, Dept Gynecol & Obstet, Bergen, Norway
Darcy L. Thull - University of Pittsburgh
Laima Tihomirova - Latvian Biomed Res & Study Ctr, Riga, Latvia
Anna V. Tinker - BC Canc Agcy, Cheryl Brown Ovarian Canc Outcomes Unit CBOCOU, Ovarian Canc Res OVCARE Program, Vancouver, BC, Canada
Marc Tischkowitz - McGill University
Silvia Tognazzo - Veneto Inst Oncol IOV IRCCS, Immunol & Mol Oncol Unit, Padua, Italy
Amanda Ewart Toland - The Ohio State University
Alicia Tone - Princess Margaret Hosp, Univ Hlth Network, Div Gynecol Oncol, Toronto, ON, Canada
Britton Trabert - NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA
Ruth C. Travis - Univ Hawaii, John A Burns Sch Med, Dept Obstet & Gynecol, Honolulu, HI 96822 USA
Antonia Trichopoulou - Univ Calif San Francisco, Canc Risk Program, San Francisco, CA 94143 USA
Nadine Tung - College Station Medical Center
Shelley S. Tworoger - Brigham & Womens Hosp, Channing Div Network Med, 75 Francis St, Boston, MA 02115 USA
Anne M. Van Altena - Radboud Univ Nijmegen, Med Ctr, Dept Obstet & Gynaecol, Div Gynecol Oncol, Nijmegen, Netherlands
David Van den Berg - Univ Southern Calif, Keck Sch Med, Dept Prevent Med, Norris Comprehens Canc Ctr, Los Angeles, CA USA
Annemarie H. van der Hout - University of Groningen
Rob B. van der Luijt - Univ Med Ctr Utrecht, Dept Med Genet, Utrecht, Netherlands
Mattias Van Heetvelde - Univ Ghent, Ctr Med Genet, Ghent, Belgium
Els Van Nieuwenhuysen - Univ Hosp Leuven, Dept Obstet & Gynaecol, Div Gynecol Oncol, Leuven, Belgium
Elizabeth J. Van Rensburg - University of Pretoria
Adriaan Vanderstichele - Univ Cambridge, Dept Publ Hlth & Primary Care, Ctr Canc Genet Epidemiol, Cambridge, England
Raymonda Varon-Mateeva - Charité - Universitätsmedizin Berlin
Ana Vega - Inst Invest Sanitaria IDIS, Fdn Publ Galega Med Xenom, Serv Galego Saude SERGAS, Santiago De Compostela, Spain
Digna Velez Edwards - Vanderbilt Univ Sch Med, Dept Med, Vanderbilt Epidemiol Ctr, Nashville, TN USA
Ignace Vergote - Univ Hosp Leuven, Dept Obstet & Gynaecol, Div Gynecol Oncol, Leuven, Belgium
Robert A. Vierkant - Mayo Clin, Div Biomed Stat & Informat, Dept Hlth Sci Res, Rochester, MN USA
Joseph Vijai - Mem Sloan Kettering Canc Ctr, Dept Med, Clin Genet Res Lab, 1275 York Ave, New York, NY 10021 USA
Athanassios Vratimos - National Centre of Scientific Research "Demokritos"
Lisa Walker - Churchill Hosp, Oxford Reg Genet Serv, Oxford, England
Christine Walsh - College Station Medical Center
Dorothea Wand - Univ Hosp, Inst Human Genet, Leipzig, Germany
Shan Wang-Gohrke - Universität Ulm
Barbara Wappenschmidt - Univ Hosp Cologne, Ctr Integrated Oncol, Ctr Familial Breast & Ovarian Canc, Cologne, Germany
Penelope M. Webb - QIMR Berghofer Med Res Inst, Populat Hlth Dept, Herston, Qld, Australia
Clarice R. Weinberg - NIEHS, Biostat & Computat Biol Branch, Div Intramural Res, US Natl Inst Hlth, POB 12233, Res Triangle Pk, NC 27709 USA
Jeffrey N. Weitzel - City of Hope
Nicolas Wentzensen - NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA
Alice S. Whittemore - Stanford Univ, Sch Med, Dept Hlth Res & Policy Epidemiol, Stanford, CA 94305 USA
Juul T. Wijnen - Leiden University
Lynne R. Wilkens - Univ Hawaii, Ctr Canc, Canc Epidemiol Program, Honolulu, HI 96822 USA
Alicja Wolk - Karolinska Inst, Dept Environm Med, Div Nutr Epidemiol, Stockholm, Sweden
Michelle Woo - Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Program Genet Epidemiol & Stat Genet, Boston, MA USA
Xifeng Wu - Univ Texas MD Anderson Canc Ctr, Dept Epidemiol, Houston, TX 77030 USA
Anna H. Wu - Univ Southern Calif, Keck Sch Med, Dept Prevent Med, Norris Comprehens Canc Ctr, Los Angeles, CA USA
Hannah Yang - NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA
Drakoulis Yannoukakos - National Centre of Scientific Research "Demokritos"
Argyrios Ziogas - Univ Calif Irvine, Dept Epidemiol, Irvine, CA USA
Kristin K. Zorn - Univ Pittsburgh, Sch Med, Dept Med, Magee Womens Hosp,UPMC, Pittsburgh, PA 15213 USA
Steven A. Narod - University of Toronto
Douglas F. Easton - Univ Cambridge, Dept Publ Hlth & Primary Care, Strangeways Res Lab, Ctr Canc Genet Epidemiol, Cambridge, England
Christopher I. Amos - Geisel Sch Med Dartmouth, Dept Biomed Data Sci, Ctr Genom Med, Lebanon, NH USA
Joellen M. Schildkraut - Univ Virginia, Dept Publ Hlth Sci, Charlottesville, VA USA
Susan J. Ramus - UNSW Sydney
Laura Ottini - Univ Roma La Sapienza, Dept Mol Med, Rome, Italy
Marc T. Goodman - College Station Medical Center
Sue K. Park - Seoul Natl Univ, Coll Med, Dept Prevent Med, Seoul, South Korea
Linda E. Kelemen - Med Univ South Carolina, Coll Med, Dept Publ Hlth Sci, Charleston, SC USA
Harvey A. Risch - Yale Sch Publ Hlth, Dept Chron Dis Epidemiol, New Haven, CT USA
Mads Thomassen - Odense Univ Hosp, Dept Clin Genet, Odense, Denmark
Kenneth Offit - Mem Sloan Kettering Canc Ctr, Dept Med, Clin Genet Res Lab, 1275 York Ave, New York, NY 10021 USA
Jacques Simard - Ctr Hosp Univ Quebec, Genom Ctr, Res Ctr, Quebec City, PQ, Canada
Rita Katharina Schmutzler - Univ Hosp Cologne, Ctr Integrated Oncol, Ctr Familial Breast & Ovarian Canc, Cologne, Germany
Dennis Hazelett - Cedars Sinai Med Ctr, Dept Biomed Sci, Los Angeles, CA USA
Alvaro N. Monteiro - H Lee Moffitt Canc Ctr & Res Inst, Dept Canc Epidemiol, Tampa, FL USA
Fergus J. Couch - Mayo Clin, Dept Lab Med & Pathol, Div Expt Pathol, Rochester, MN USA
Andrew Berchuck - Duke Univ, Med Ctr, Dept Obstet & Gynecol, Durham, NC 27710 USA
Georgia Chenevix-Trench - QIMR Berghofer Med Res Inst, Dept Genet & Computat Biol, Brisbane, Qld, Australia
Ellen L. Goode - Mayo Clin, Div Epidemiol, Dept Hlth Sci Res, Rochester, MN USA
Thomas A. Sellers - H Lee Moffitt Canc Ctr & Res Inst, Dept Canc Epidemiol, Tampa, FL USA
Simon A. Gayther - College Station Medical Center
Antonis C. Antoniou - Univ Cambridge, Dept Publ Hlth & Primary Care, Strangeways Res Lab, Ctr Canc Genet Epidemiol, Cambridge, England
Paul D. P. Pharoah - Univ Cambridge, Dept Publ Hlth & Primary Care, Strangeways Res Lab, Ctr Canc Genet Epidemiol, Cambridge, England
KConFab Investigators
Détails de publication: Nature genetics, Vol.49(5), pp.680-691
Éditeur: NATURE PORTFOLIO
Nombre de pages: 12
Note de subvention: Odense University Hospital Research Foundation 10124 / Cancer Research UK; The Francis Crick Institute; Cancer Research UK IG16933 / Italian Association for Cancer Research; Fondazione AIRC per la ricerca sul cancro CA1X01HG007491-01; U19-CA148112; R01-CA149429; R01-CA058598 / US National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA G0601891 / MRC; UK Research & Innovation (UKRI); Medical Research Council UK (MRC) Ovarian Cancer Research Fund Ministere de l'Economie, de la Science et de l'Innovation du Quebec through Genome Quebec Quebec Breast Cancer Foundation 15973; 23382; 16561; 12677; 20861; 16491 / Cancer Research UK 1420190 / National RAMP;D Program for Cancer Control, Ministry of Health and Welfare, Republic of Korea
Identifiants: 99158936109311
Unité académique: Maladies Infectieuses et Vecteurs : Ecologie, Génétique, Evolution et Contrôle - MIVEGEC
Langue: English
Type de ressource: Journal article