Human tumor-derived exosomes (TEX) regulate Treg functions via cell surface signaling rather than uptake mechanisms

Journal article

Open access

Peer reviewed

Laurent Muller, Patricia Simms, Chang-Sook Hong, Michael Nishimura, Edwin Jackson, Simon Watkins and Theresa L Whiteside

OncoImmunology, Vol.6(8)

07/04/2017

PMCID: PMC5593709

PMID: 28919985

Abstract

Ca2+ flux

T cell subsets

exosome uptake

regulatory T cells

tumor-derived exosomes

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Title: Human tumor-derived exosomes (TEX) regulate Treg functions via cell surface signaling rather than uptake mechanisms
Creators - without role: Laurent Muller - University Hospital of Basel
Patricia Simms - Loyola University Chicago
Chang-Sook Hong - University of Pittsburgh School of Medicine
Michael Nishimura - Loyola University Chicago
Edwin Jackson - University of Pittsburgh
Simon Watkins - UPMC Hillman Cancer Center
Theresa L Whiteside - UPMC Hillman Cancer Center
Publication Details: OncoImmunology, Vol.6(8)
Identifiers: 9943143309311
Academic Unit: Initial MAnagement & prevent of acute orGan failures IN critically ill patiEnts - IMAGINE
Language: English
Resource Type: Journal article
Local Fields: hal-01800329