Hollow Organosilica Nanoparticles for Drug Delivery

Saher Rahmani; Alia Akrout; Jelena Budimir; Dina Aggad; Morgane Daurat; Anastasia Godefroy; Christophe Nguyen; Hanene Largot; Magali Gary-Bobo; Laurence Raehm; Jean-Olivier Durand; Clarence Charnay

doi:10.1002/slct.201802107

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Hollow Organosilica Nanoparticles for Drug Delivery

Journal article

Peer reviewed

Hollow Organosilica Nanoparticles for Drug Delivery

Saher Rahmani, Alia Akrout, Jelena Budimir, Dina Aggad, Morgane Daurat, Anastasia Godefroy, Christophe Nguyen, Hanene Largot, Magali Gary-Bobo, Laurence Raehm, …

ChemistrySelect, Vol.3(37), pp.10439 - 10442

09/10/2018

DOI: https://doi.org/10.1002/slct.201802107

Abstract

Gemcitabine

MCF-7 breast cancer cells

Methotrexate

Organosilica Nanoparticles

The sol‐gel synthesis of hollow organosilica nanoparticles incorporating amino groups with uniform size are described. These nanoparticles were successfully prepared via a microemulsion method. Then, the hollow nanoparticles were loaded with gemcitabine hydrochloride or methotrexate and studied in MCF‐7 breast cancer cells.

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Title: Hollow Organosilica Nanoparticles for Drug Delivery
Creators - without role: Saher Rahmani - Université de Montpellier, Institut Charles Gerhardt Montpellier - ICGM
Alia Akrout - Université de Montpellier, Institut Charles Gerhardt Montpellier - ICGM
Jelena Budimir - Université de Montpellier, Institut Charles Gerhardt Montpellier - ICGM
Dina Aggad - Université de Montpellier, Institut des Biomolécules Max Mousseron - IBMM
Morgane Daurat - Université de Montpellier, Institut des Biomolécules Max Mousseron - IBMM
Anastasia Godefroy - Institut des Biomolécules Max Mousseron
Christophe Nguyen - Université de Montpellier, Institut des Biomolécules Max Mousseron - IBMM
Hanene Largot - Université de Montpellier, Institut Charles Gerhardt Montpellier - ICGM
Magali Gary-Bobo - Université de Montpellier, Institut des Biomolécules Max Mousseron - IBMM
Laurence Raehm - Université de Montpellier, Institut Charles Gerhardt Montpellier - ICGM
Jean-Olivier Durand - Université de Montpellier, Institut Charles Gerhardt Montpellier - ICGM
Clarence Charnay - Université de Montpellier, Institut Charles Gerhardt Montpellier - ICGM
Publication Details: ChemistrySelect, Vol.3(37), pp.10439 - 10442
Identifiers: 9945250709311
Academic Unit: Institut Charles Gerhardt Montpellier - ICGM; Institut des Biomolécules Max Mousseron - IBMM
Language: English
Resource Type: Journal article
Local Fields: hal-01902727