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High Failure Rate of the ViroSeq HIV-1 Genotyping System for Drug Resistance Testing in Cameroon, a Country with Broad HIV-1 Genetic Diversity
Article de revue   Avec comité de lecture

High Failure Rate of the ViroSeq HIV-1 Genotyping System for Drug Resistance Testing in Cameroon, a Country with Broad HIV-1 Genetic Diversity

Avelin Aghokeng, Eitel Mpoudi-Ngole, Julius Chia, Elvine Edoul, Eric Delaporte et Martine Peeters
Journal of clinical microbiology, Vol.49(4), pp.1635-1641
01/04/2011
PMID: 21270223

Résumé

Human health and pathology Infectious diseases Life Sciences Microbiology and Parasitology Virology
The ViroSeq HIV-1 genotyping system is used in many African countries for drug resistance testing. In this study, we used a panel of diverse HIV-1 group M isolates circulating in Cameroon to show that the performance of this assay can be altered by the sequence variation of non-B HIV-1 strains that predominate in African settings.

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