Herpes simplex virus hepatitis in patients requiring intensive care unit admission: a retrospective, multicenter, observational study

Thomas Frapard; Giuliana Amaddeo; Maxens Decavèle; Paer-Selim Abback; Antoine Gaillet; Charlotte Bouzbib; Claire Vanlemmens; Romy Younan; Emmanuel Canet; Anne-Sophie Moreau; Mathilde Neuville; Élie Azoulay; Alexandre Sitbon; Djamel Mokart; Sylvie Radenne; Armand Abergel; Céline Guichon; Olivier Roux; Agnès Bonadona; Armand Mekontso-Dessap; Audrey de Jong; Jérôme Dumortier; Nicolas de Prost

doi:10.1093/ofid/ofad484

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Herpes simplex virus hepatitis in patients requiring intensive care unit admission: a retrospective, multicenter, observational study

Journal article

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Herpes simplex virus hepatitis in patients requiring intensive care unit admission: a retrospective, multicenter, observational study

Thomas Frapard, Giuliana Amaddeo, Maxens Decavèle, Paer-Selim Abback, Antoine Gaillet, Charlotte Bouzbib, Claire Vanlemmens, Romy Younan, Emmanuel Canet, Anne-Sophie Moreau, …

Open Forum Infectious Diseases, Vol.10(11)

11/2023

DOI: https://doi.org/10.1093/ofid/ofad484

PMCID: PMC10629341

PMID: 37942463

Abstract

The clinical features and short-term prognosis of patients admitted to the intensive care unit for herpes hepatitis are lacking. On 33 patients admitted between 2006 and 2022, 22 were immunocompromised, 4 were pregnant women, 23 died. 16 patients developed a hemophagocytic syndrome. Aciclovir was initiated 1 day [0-3] after admission.

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Title: Herpes simplex virus hepatitis in patients requiring intensive care unit admission: a retrospective, multicenter, observational study
Creators - without role: Thomas Frapard - Hôpitaux Universitaires Henri-Mondor
Giuliana Amaddeo - Assistance Publique – Hôpitaux de Paris
Maxens Decavèle - Neurophysiologie respiratoire expérimentale et clinique
Paer-Selim Abback - Centre Hospitalier Universitaire de Tours
Antoine Gaillet - Hôpitaux Universitaires Henri-Mondor
Charlotte Bouzbib - Assistance Publique – Hôpitaux de Paris
Claire Vanlemmens - Centre Hospitalier Universitaire de Besançon
Romy Younan - Assistance Publique – Hôpitaux de Paris
Emmanuel Canet - Centre Hospitalier Universitaire de Nantes
Anne-Sophie Moreau - Centre Hospitalier Universitaire de Lille
Mathilde Neuville - Hôpital Foch
Élie Azoulay - Hôpital Saint-Louis
Alexandre Sitbon - Assistance Publique – Hôpitaux de Paris
Djamel Mokart - Institut Paoli-Calmettes
Sylvie Radenne - Hôpital de la Croix-Rousse
Armand Abergel - Centre Hospitalier Universitaire de Clermont-Ferrand
Céline Guichon - Hôpital de la Croix-Rousse
Olivier Roux - Hôpital Beaujon
Agnès Bonadona - Centre Hospitalier Universitaire de Grenoble
Armand Mekontso-Dessap - Centre Hospitalier Universitaire Henri-Mondor
Audrey de Jong - Université de Montpellier, Physiologie et Médecine Expérimentale du coeur et des muscles - PhyMedExp
Jérôme Dumortier - Hôpital Edouard Herriot
Nicolas de Prost - Hôpitaux Universitaires Henri-Mondor
Publication Details: Open Forum Infectious Diseases, Vol.10(11)
Identifiers: 9937460409311
Academic Unit: Physiologie et Médecine Expérimentale du coeur et des muscles - PhyMedExp
Language: English
Resource Type: Journal article
Local Fields: hal-04234309