Résumé
In France, therapeutic patient education is a cornerstone of posttransplant care. However, substantial variability persists in how immunosuppressive therapies are addressed across transplant centers, potentially affecting adherence and patient outcomes. To reduce this heterogeneity, the French-Speaking Society for Transplantation (Société Francophone de Transplantation) launched a national initiative to harmonize educational practices on immunosuppressive therapy. Following a national survey that highlighted inconsistent and sometimes conflicting messages delivered to patients, a multidisciplinary working group comprising transplant physicians, pharmacists, pharmacologists, nurses, and representatives of patient associations developed a practical reference guide. This guide aims to help healthcare teams deliver coherent, evidence-based messages on key aspects of immunosuppressant management. Adaptable to local workflows and patient needs, it covers 7 core domains: timing of administration; relation to meals; missed-dose management; food and drug interactions; travel across time zones; handling of dosage forms; and special situations such as vomiting or swallowing disorders. It also underscores the critical role of therapeutic drug monitoring in supporting individualized care and strengthening adherence. This nationally coordinated initiative illustrates how collaborative, cross-disciplinary efforts can enhance the quality and consistency of patient education in transplantation. Its structured approach may serve as a model for other countries seeking to optimize adherence and long-term outcomes through standardized educational practices.