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Glutamic acid as a new linker for attachment of alcohols to solid support
Article de revue   Avec comité de lecture

Glutamic acid as a new linker for attachment of alcohols to solid support

Gilles Subra, Muriel Amblard et Jean Martinez
Tetrahedron letters, Vol.43(50), pp.9221-9223
09/12/2002
DOI: https://doi.org/10.1016/S0040-4039(02)02209-8

Résumé

combinatorial chemistry glutamic acid linker solid-phase synthesis
We took advantage of pyroglutamic cyclization of glutamic acid to investigate the use of this amino acid as a linker for the attachment of alcohols. As a first example, we reported the solid-phase synthesis of dimers on a 3,3′-diaminodiphenylmethanol. Graphic

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