Résumé
A total of 4940 random sequence tags of the dimorphic yeast
Yarrowia lipolytica, totalling 4.9 Mb, were analyzed. BLASTX comparisons revealed at least 1229 novel
Y. lipolytica genes 1083 genes having homology with
Saccharomyces cerevisiae genes and 146 with genes from various other genomes. This confirms the rapid sequence evolution assumed for
Y. lipolytica. Functional analysis of newly discovered genes revealed that several enzymatic activities were increased compared to
S. cerevisiae, in particular, transport activities, ion homeostasis, and various metabolism pathways. Most of the mitochondrial genes were identified in contigs spanning more than 47 kb. Matches to retrotransposons were observed, including a
S. cerevisiae Ty3 and a LINE element. The sequences have been deposited with EMBL under the accession numbers
AL409956–
AL414895.