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Genetic variability within Trypanosoma brucei gambiense: evidence for the circulation of different genotypes in human African trypanosomiasis patients in Côte d'Ivoire
Article de revue   Avec comité de lecture

Genetic variability within Trypanosoma brucei gambiense: evidence for the circulation of different genotypes in human African trypanosomiasis patients in Côte d'Ivoire

Philippe Truc, Sophie Ravel, Vincent Jamonneau, Paul N'Guessan et Gérard Cuny
Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol.96(1), pp.52-55
01/01/2002
DOI: https://doi.org/10.1016/S0035-9203(02)90237-3
PMID: 11925992

Résumé

Côte d'Ivoire genetic variability genotypes microsatellites mixed infection Trypanosoma brucei gambiense trypanosomiasis
For 23 Ivoirian patients infected by Trypanosoma brucei gambiense, isolation and genetic characterization using PCR and microsatellite primers were performed (in 1996–1999) using 2 different isolates (A and B) from each patient. When using TBDAC 1/2, 7 genotypes were observed, and DNAs A and B for 2 patients were different. This might be the first evidence of the presence of 2 different genotypes of T. b. gambiense group 1 in the same patient.

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