Fungal Integrated Histomolecular Diagnosis Using Targeted Next-Generation Sequencing on Formalin-Fixed Paraffin-Embedded Tissues

Alexis Trecourt; Meja Rabodonirina; Claire Mauduit; Alexandra Traverse-Glehen; Mojgan Devouassoux-Shisheboran; David Meyronet; Frédérique Dijoud; Christophe Ginevra; Emmanuelle Chapey-Picq; Emilie Josse; Patricia Martins-Simoes; Patricia Martins Simões; Abderrazzak Bentaher; Damien Dupont; Charline Miossec; Florence Persat; Martine Wallon; Tristan Ferry; Félix Pham; Bruno Simon; Jean Menotti

doi:10.1128/jcm.01520-22

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Fungal Integrated Histomolecular Diagnosis Using Targeted Next-Generation Sequencing on Formalin-Fixed Paraffin-Embedded Tissues

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Fungal Integrated Histomolecular Diagnosis Using Targeted Next-Generation Sequencing on Formalin-Fixed Paraffin-Embedded Tissues

Alexis Trecourt, Meja Rabodonirina, Claire Mauduit, Alexandra Traverse-Glehen, Mojgan Devouassoux-Shisheboran, David Meyronet, Frédérique Dijoud, Christophe Ginevra, Emmanuelle Chapey-Picq, Emilie Josse, …

Journal of Clinical Microbiology, Vol.61(3)

23/03/2023

DOI: https://doi.org/10.1128/jcm.01520-22

Résumé

Histopathology is the gold standard for fungal infection (FI) diagnosis, but it does not provide a genus and/or species identification. The objective of the present study was to develop targeted next-generation sequencing (NGS) on formalin-fixed tissue samples (FTs) to achieve a fungal integrated histomolecular diagnosis.

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Titre: Fungal Integrated Histomolecular Diagnosis Using Targeted Next-Generation Sequencing on Formalin-Fixed Paraffin-Embedded Tissues
Créateurs - sans rôle: Alexis Trecourt - Hôpital Lyon Sud
Meja Rabodonirina - Hospices Civils de Lyon
Claire Mauduit - Centre Méditerranéen de Médecine Moléculaire
Alexandra Traverse-Glehen - Inserm
Mojgan Devouassoux-Shisheboran - Hospices Civils de Lyon
David Meyronet - Université Claude Bernard Lyon 1
Frédérique Dijoud - Université Claude Bernard Lyon 1
Christophe Ginevra - Hospices Civils de Lyon
Emmanuelle Chapey-Picq
Emilie Josse - Université de Montpellier, Physiologie et Médecine Expérimentale du coeur et des muscles - PhyMedExp
Patricia Martins-Simoes - Hospices Civils de Lyon
Patricia Martins Simões - Hospices Civils de Lyon
Abderrazzak Bentaher - Université Claude Bernard Lyon 1
Damien Dupont - Université Claude Bernard Lyon 1
Charline Miossec - Hospices Civils de Lyon
Florence Persat - Hospices Civils de Lyon
Martine Wallon - Université Claude Bernard Lyon 1
Tristan Ferry - Hospices Civils de Lyon
Félix Pham - Hôpital Lyon Sud
Bruno Simon - Hospices Civils de Lyon
Jean Menotti - Hospices Civils de Lyon
Détails de publication: Journal of Clinical Microbiology, Vol.61(3)
Identifiants: 99150165609311
Unité académique: Physiologie et Médecine Expérimentale du coeur et des muscles - PhyMedExp
Langue: English
Type de ressource: Journal article
Champs locaux: hal-04926203