First synthesis of the enantiomerically pure α-hydroxy analogue of S- tert-butyl cysteine

Florine Cavelier

doi:10.1016/S0957-4166(96)00471-5

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First synthesis of the enantiomerically pure α-hydroxy analogue of S- tert-butyl cysteine

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First synthesis of the enantiomerically pure α-hydroxy analogue of S- tert-butyl cysteine

Florine Cavelier

Tetrahedron: asymmetry, Vol.8(1), pp.41-43

09/01/1997

DOI: https://doi.org/10.1016/S0957-4166(96)00471-5

Résumé

The first synthesis of enantiomerically pure 2-hydroxy 3- tert-butylthio propionic acid in a one-pot reaction from chiral glycidate has been achieved with total conservation of stereochemistry. We report the first synthesis of enantiomerically pure 2-hydroxy 3- tert-butylthio propionic acid in a one-pot reaction from chiral glycidate with total conservation of stereochemistry. The targeted compound 3 was purified by preparative HPLC and fully characterised for the first time.

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Détails

Titre: First synthesis of the enantiomerically pure α-hydroxy analogue of S- tert-butyl cysteine
Créateurs - sans rôle: Florine Cavelier - Laboratoire des Aminoacides, Peptides et Protéines (LAPP), ESA-CNRS 5075, Université Montpellier II, 34095 Montpellier Cedex 05, France
Détails de publication: Tetrahedron: asymmetry, Vol.8(1), pp.41-43
Éditeur: Elsevier Ltd
Nombre de pages: 3
Identifiants: 99163057509311
Unité académique: Institut des Biomolécules Max Mousseron - IBMM
Langue: English
Type de ressource: Journal article