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First report of knockdown mutations in the malaria vector Anopheles gambiae from Cameroon.
Journal article   Open access   Peer reviewed

First report of knockdown mutations in the malaria vector Anopheles gambiae from Cameroon.

Josiane Etang, Etienne Fondjo, Fabrice Chandre, Isabelle Morlais, Cecile Brengues, Philippe Nwane, Mouhamadou Chouaibou, Hamadou Ndjemai and Frédéric Simard
American Journal of Tropical Medicine and Hygiene, Vol.74(5), pp.795-7
01/05/2006
DOI: https://doi.org/10.4269/ajtmh.2006.74.795
PMID: 16687682

Abstract

Animals Anopheles Malaria Mosquito Control Mutation Pyrethrins Cameroon DDT Humans Insect Vectors Insecticide Resistance Insecticides
We report the first finding of the knockdown Leu-Phe and Leu-Ser mutations associated with resistance to pyrethroids and DDT insecticides in the malaria mosquito Anopheles gambiae from Cameroon. The Leu-Phe mutation was found in both the M and S molecular forms of An. gambiae. Importantly, two specimens of the S molecular form were found to carry both mutations in a heterozygous state.
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