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Expression of a truncated v-myb product in transformed chicken embryo fibroblasts
Article de revue   Avec comité de lecture

Expression of a truncated v-myb product in transformed chicken embryo fibroblasts

Cécile Kryceve-Martinerie, Johann Soret, Janine Crochet, Marcel Baluda et Bernard Perbal
FEBS letters, Vol.214(1), pp.81-86
06/04/1987
PMID: 3032682

Résumé

Avian Fibroblast Myeloblastosis Transformation V-myb oncogene
Transformed cells have been isolated after transfection of chicken embryo fibroblasts (CEF) with the DNA of a recombinant clone (KXA 3457) in which the v-myb sequences are flanked by the two AMV-LTRs. Abnormal myb-specific RNA species and myb-related polypeptides were found to be expressed in these cells, suggesting that transformation of CEF by v-myb might require alterations of the oncogene product.

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