Enzymatic peptide synthesis in organic solvent mediated by gels of copolymerized acrylic derivatives of α‐chymotrypsin and polyoxyethylene

Valérie Rolland; Robert Jacquier; René Lazaro; Philippe Viallefont

doi:10.1111/j.1399-3011.1991.tb01439.x

Retour

Enzymatic peptide synthesis in organic solvent mediated by gels of copolymerized acrylic derivatives of α‐chymotrypsin and polyoxyethylene

Article de revue

Avec comité de lecture

Enzymatic peptide synthesis in organic solvent mediated by gels of copolymerized acrylic derivatives of α‐chymotrypsin and polyoxyethylene

Valérie Rolland, Robert Jacquier, René Lazaro et Philippe Viallefont

International journal of peptide and protein research, Vol.38(3), pp.273-277

09/1991

DOI: https://doi.org/10.1111/j.1399-3011.1991.tb01439.x

PMID: 1761373

Résumé

Catalysis

Chemical Sciences

Medicinal Chemistry

Organic chemistry

Polymers

Copolymers of acrylated derivatives of α‐chymotrypsin and polyethylene glycol (PEG) have been prepared and used as biocatalysts for the synthesis of model peptides in organic solvent containing a low quantity of water. Other peptide couplings have been tried to point out the chemico‐ and stereoselectivity and examples of segment couplings are given.

Indicateurs

1 Consultations de la notice

Détails

Titre: Enzymatic peptide synthesis in organic solvent mediated by gels of copolymerized acrylic derivatives of α‐chymotrypsin and polyoxyethylene
Créateurs - sans rôle: Valérie Rolland - Laboratoire d'aminoacides et peptides
Robert Jacquier - Laboratoire d'aminoacides et peptides
René Lazaro - Laboratoire d'aminoacides et peptides
Philippe Viallefont - Laboratoire d'aminoacides et peptides
Détails de publication: International journal of peptide and protein research, Vol.38(3), pp.273-277
Éditeur: Wiley
Nombre de pages: 5
Identifiants: 99139012509311
Unité académique: Institut des Biomolécules Max Mousseron - IBMM
Langue: English
Type de ressource: Journal article