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Enzymatic esterification and transesterification of N-protected Glu or Asp and synthesis of sweetener aspartam analogues by a new glutamic acid specific endopeptidase
Journal article   Open access   Peer reviewed

Enzymatic esterification and transesterification of N-protected Glu or Asp and synthesis of sweetener aspartam analogues by a new glutamic acid specific endopeptidase

Philippe Viallefont, René Lazaro and Valérie Rolland-Fulcrand
Catalysis Letters, Vol.27(1-2), pp.235-240
1994

Abstract

glutamic acid specific endopeptidase (BL-GSE) esterification transesterification peptide synthesis sweetener aspartam analogues
Esterification and transesterification reactions are carried out in water miscible organic solvents by using a new glutamic acid specific endopeptidase, isolated from Bacillus licheniformis. Sweetener aspartam analogues syntheses are also described.
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