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Enantioselectivity induced by oxazaborolidine supported on mesoporous silica or by its analog in homogeneous phase
Journal article   Open access   Peer reviewed

Enantioselectivity induced by oxazaborolidine supported on mesoporous silica or by its analog in homogeneous phase

Jeremy Yune, Françoise Quignard and Karine Molvinger
Molecules, Vol.15, pp.3643-3660
18/05/2010

Abstract

oxazaborolidine supported catalyst mesoporous silica asymmetric reduction of acetophenone
The impact of immobilization of oxazaborolidines supported on silica via different substituents on the boron and nitrogen atoms is evaluated in the enantioselective reduction of acetophenone. The performances of the homogeneous analog oxazaborolidines and silica supported-ones are compared by varying different parameters. This article deals with the synthesis, characterization and catalytic evaluation of silica-supported oxazaborolidines, their recycling capabilities and regeneration limitations
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