Logo image
Se connecter
Electrophilic Activation of Amides for the Preparation of Polysubstituted Pyrimidines
Article de revue   Avec comité de lecture

Electrophilic Activation of Amides for the Preparation of Polysubstituted Pyrimidines

Tobias Stopka, Pauline Adler, Gerhard Hagn, Haoqi Zhang, Veronica Tona et Nuno Maulide
Synthesis (Stuttgart), Vol.51(1), pp.194-202
01/01/2019

Résumé

Chemistry Chemistry, Organic Physical Sciences Science & Technology
In this article we describe the straightforward synthesis of polysubstituted pyrimidines by electrophilic activation of secondary amides in the presence of alkynes. An unusual mechanistic detour leading to pyridine derivatives as products is also presented and briefly discussed.

Indicateurs

1 Consultations de la notice

Détails

Logo image