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Efficient synthesis of bromoacetylated wang resin
Article de revue   Avec comité de lecture

Efficient synthesis of bromoacetylated wang resin

André Nouvet, Frédéric Lamaty et René Lazaro
Tetrahedron letters, Vol.39(21), pp.3469-3470
21/05/1998

Résumé

P(Ph)3/DEAD PEG PS DCC DMAP TFA IBCF DIC
The alcohol groups linked to different polymers have been subjected to bromoacetylation either by alcohol activation (under Mitsunobu conditions) or by several acid- activation methods. By far the best result for Wang resin was obtained with the first strategy.

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