Efficacy and safety of tezepelumab versus placebo in adults with moderate to very severe chronic obstructive pulmonary disease (COURSE): a randomised, placebo-controlled, phase 2a trial

Dave Singh; Christopher Brightling; Klaus Rabe; Meilan Han; Stephanie Christenson; M Bradley Drummond; Alberto Papi; Ian Pavord; Nestor Molfino; Gun Almqvist; Ales Kotalik; Åsa Hellqvist; Monika Gołąbek; Navreet Sindhwani; Sandhia Ponnarambil; Jasmin Belle-Isle; Jerome Nadeau; William Killorn; Bruno Francoeur; Emilie Millaire; Bonavuth Pek; Murdo Ferguson; Francois Maltais; Kieran Killian; Giuseppe Mazza; Lyle Melenka; Brandie Walker; Celine Bergeron; John Fitzgerald; Ulla Møller Weinreich; Elisabeth Bendstrup; Celeste Porsbjerg; Charlotte Ulrik; Ingrid Titlestad; Christian Meyer; Ole Hilberg; Francis Couturaud; Claire Andrejak; Arnaud Bourdin; Gilles Devouassoux; Jean-Louis Pepin; Pascal Chanez; Arnaud Cavailles; Andreas Eich; Andrea Ludwig-Sengpiel; Henrik Watz; Thomas Schultz; Amir Bar-Shai; Ori Wand; Yochai Adir; Neville Berkman; Gershon Fink; David Shitrit; Gabriel Izbicki; Yael Raviv; Pascal Wielders; Martijn Goosens; Roxane Heller-Baan; Johannes In'T Veen; Frank Custers; Yeon-Mok Oh; Yongchul Lee; Jaeyeol Kim; Kwang-Ha Yoo; Jung-Won Park; Sang Haak Lee; Joong Hyun Ahn; Sook Young Lee; Jin Woo Kim; Kwan Ho Lee; Luis Mateos Caballero; Elsa Naval Sendra; David Ramos Barbón; José Luis Velasco Garrido; Bernardino Alcázar Navarrete; Dinesh Saralaya; Michael Crooks; Pallav Shah; Rekha Chaudhuri; Anthony de Soyza; Monica Nordstrom; Akshay Dwarakanath; Steven Weinstein; David Pham; John Mitchell; Selwyn Spangenthal; Sever Surdulescu; Michael Denenberg; Sady Alpizar; David Maybee; Timothy Moriarty; Faisal Fakih; Richard Beasley; Marvin Heuer; Amit Patel; Jeffrey Dorf; Rafael Martinez; Shahrukh Kureishy; Ryan Klein; Mitzie Hewitt; Jeremy Cole; Emory Robinette; Edward Cordasco; Robert Garver; Gerard Criner; Frank Sciurba; Edward Kerwin; Gregg Lucksinger; John Delgado; David Russian; Geoffrey Chupp

doi:10.1016/S2213-2600(24)00324-2

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Efficacy and safety of tezepelumab versus placebo in adults with moderate to very severe chronic obstructive pulmonary disease (COURSE): a randomised, placebo-controlled, phase 2a trial

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Efficacy and safety of tezepelumab versus placebo in adults with moderate to very severe chronic obstructive pulmonary disease (COURSE): a randomised, placebo-controlled, phase 2a trial

Dave Singh, Christopher Brightling, Klaus Rabe, Meilan Han, Stephanie Christenson, M Bradley Drummond, Alberto Papi, Ian Pavord, Nestor Molfino, Gun Almqvist, …

The Lancet Respiratory Medicine

12/2024

DOI: https://doi.org/10.1016/S2213-2600(24)00324-2

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Title: Efficacy and safety of tezepelumab versus placebo in adults with moderate to very severe chronic obstructive pulmonary disease (COURSE): a randomised, placebo-controlled, phase 2a trial
Creators - without role: Dave Singh
Christopher Brightling
Klaus Rabe
Meilan Han
Stephanie Christenson
M Bradley Drummond
Alberto Papi
Ian Pavord
Nestor Molfino
Gun Almqvist
Ales Kotalik
Åsa Hellqvist
Monika Gołąbek
Navreet Sindhwani
Sandhia Ponnarambil
Jasmin Belle-Isle
Jerome Nadeau
William Killorn
Bruno Francoeur
Emilie Millaire
Bonavuth Pek
Murdo Ferguson
Francois Maltais
Kieran Killian
Giuseppe Mazza
Lyle Melenka
Brandie Walker
Celine Bergeron
John Fitzgerald
Ulla Møller Weinreich
Elisabeth Bendstrup
Celeste Porsbjerg
Charlotte Ulrik
Ingrid Titlestad
Christian Meyer
Ole Hilberg
Francis Couturaud
Claire Andrejak
Arnaud Bourdin - Université de Montpellier, Physiologie et Médecine Expérimentale du coeur et des muscles - PhyMedExp
Gilles Devouassoux
Jean-Louis Pepin
Pascal Chanez
Arnaud Cavailles
Andreas Eich
Andrea Ludwig-Sengpiel
Henrik Watz
Thomas Schultz
Amir Bar-Shai
Ori Wand
Yochai Adir
Neville Berkman
Gershon Fink
David Shitrit
Gabriel Izbicki
Yael Raviv
Pascal Wielders
Martijn Goosens
Roxane Heller-Baan
Johannes In'T Veen
Frank Custers
Yeon-Mok Oh
Yongchul Lee
Jaeyeol Kim
Kwang-Ha Yoo
Jung-Won Park
Sang Haak Lee
Joong Hyun Ahn
Sook Young Lee
Jin Woo Kim
Kwan Ho Lee
Luis Mateos Caballero
Elsa Naval Sendra
David Ramos Barbón
José Luis Velasco Garrido
Bernardino Alcázar Navarrete
Dinesh Saralaya
Michael Crooks
Pallav Shah
Rekha Chaudhuri
Anthony de Soyza
Monica Nordstrom
Akshay Dwarakanath
Steven Weinstein
David Pham
John Mitchell
Selwyn Spangenthal
Sever Surdulescu
Michael Denenberg
Sady Alpizar
David Maybee
Timothy Moriarty
Faisal Fakih
Richard Beasley
Marvin Heuer
Amit Patel
Jeffrey Dorf
Rafael Martinez
Shahrukh Kureishy
Ryan Klein
Mitzie Hewitt
Jeremy Cole
Emory Robinette
Edward Cordasco
Robert Garver
Gerard Criner
Frank Sciurba
Edward Kerwin
Gregg Lucksinger
John Delgado
David Russian
Geoffrey Chupp
Publication Details: The Lancet Respiratory Medicine
Identifiers: 9941500109311
Academic Unit: Physiologie et Médecine Expérimentale du coeur et des muscles - PhyMedExp
Language: English
Resource Type: Journal article
Local Fields: hal-04826386