Résumé
The antiphospholipid syndrome (APS) was described in 1983 as a systemic autoimmune disease characterized by the presence of thrombotic events or gestational morbidity in people carrying antiphospholipid antibodies (aPL). Although the disease was mainly detected in patients who already suffered from other autoimmune diseases, such as systemic lupus erythematosus (SLE), it was soon perceived that people with APS who did not suffer from other autoimmune diseases constituted a clearly differentiated clinical entity -the so called primary APS (PAPS)