Abstract
During herbivory, chewing insects deposit complex oral secretions (OS) onto the plant wound.Understanding how plants respond to the different cues of herbivory remains an active areaof research. In this study, we used an herbivory-mimick experiment to investigate the earlytranscriptional response of rice plants leaves to wounding, OS, and OS microbiota from Spodopterafrugiperda larvae. Wounding induced a massive early response associated to hormones such asjasmonates. This response switched drastically upon OS treatment indicating the activation of OSspecific pathways. When comparing native and dysbiotic OS treatments, we observed few generegulation. This suggests that in addition to wounding the early response in rice is mainly driven bythe insect compounds of the OS rather than microbial. However, microbiota affected genes encodingkey phytohormone synthesis enzymes, suggesting an additional modulation of plant response by OSmicrobiota.