Disruption of calcium transfer from ER to mitochondria links alterations of mitochondria-associated ER membrane integrity to hepatic insulin resistance

Jennifer Rieusset; J. Fauconnier; Mélanie Paillard; Elise Belaidi; Emily Tubbs; Marie-Agnès Chauvin; Annie Durand; Amélie Bravard; Geoffrey Teixeira; Birke Bartosch; Maud Michelet; Pierre Theurey; Guillaume Vial; Marie Demion; Emilie Blond; Fabien Zoulim; Ludovic Gomez; Hubert Vidal; Alain Lacampagne; Michel Ovize

doi:10.1007/s00125-015-3829-8

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Disruption of calcium transfer from ER to mitochondria links alterations of mitochondria-associated ER membrane integrity to hepatic insulin resistance

Journal article

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Disruption of calcium transfer from ER to mitochondria links alterations of mitochondria-associated ER membrane integrity to hepatic insulin resistance

Jennifer Rieusset, J. Fauconnier, Mélanie Paillard, Elise Belaidi, Emily Tubbs, Marie-Agnès Chauvin, Annie Durand, Amélie Bravard, Geoffrey Teixeira, Birke Bartosch, …

Diabetologia, Vol.59(3), pp.614-623

03/2016

DOI: https://doi.org/10.1007/s00125-015-3829-8

PMID: 26660890

Abstract

Liver

Inositol 1 4 5-triphosphate receptor

Insulin resistance

PKCε

Mitochondria-associated endoplasmic reticulum membranes

Cyclophilin D

Calcium signalling

Endoplasmic reticulum

Mitochondria

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Title: Disruption of calcium transfer from ER to mitochondria links alterations of mitochondria-associated ER membrane integrity to hepatic insulin resistance
Creators - without role: Jennifer Rieusset - Inserm
J. Fauconnier - Université de Montpellier, Physiologie et Médecine Expérimentale du coeur et des muscles - PhyMedExp
Mélanie Paillard - Inserm
Elise Belaidi - Inserm
Emily Tubbs - Inserm
Marie-Agnès Chauvin - Cardiovasculaire, métabolisme, diabétologie et nutrition
Annie Durand - Inserm
Amélie Bravard - Inserm
Geoffrey Teixeira - Inserm
Birke Bartosch - Centre de Recherche en Cancérologie de Lyon
Maud Michelet - Inserm
Pierre Theurey - Inserm
Guillaume Vial - Inserm
Marie Demion - Université de Montpellier, Physiologie et Médecine Expérimentale du coeur et des muscles - PhyMedExp
Emilie Blond - Hospices Civils de Lyon
Fabien Zoulim - Centre de Recherche en Cancérologie de Lyon
Ludovic Gomez - Inserm
Hubert Vidal - Inserm
Alain Lacampagne - Université de Montpellier, Physiologie et Médecine Expérimentale du coeur et des muscles - PhyMedExp
Michel Ovize - Hospices Civils de Lyon
Publication Details: Diabetologia, Vol.59(3), pp.614-623
Identifiers: 9939149409311
Academic Unit: Physiologie et Médecine Expérimentale du coeur et des muscles - PhyMedExp
Language: English
Resource Type: Journal article
Local Fields: hal-01786231