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Developmental signalling: A careful balancing act
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Developmental signalling: A careful balancing act

Patrick Lemaire et Hitoyoshi Yasuo
Current biology, Vol.8(7), pp.R228-R231
26/03/1998
PMID: 9545187

Résumé

Embryos of arthropods and chordates are patterned along the dorso-ventral axis by a gradient of secreted morphogens of the Bmp4/Dpp family. This gradient now appears to be shaped by the opposing activities of Bmp-sequestering proteins, on the one hand, and Bmp-releasing metalloproteases, on the other.

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