Development of a humanized in vitro blood-brain barrier model to screen for brain penetration of antiepileptic drugs

Article de revue

Avec comité de lecture

Luca Cucullo, Mohammed Hossain, Ed Rapp, Toby Manders, Nicola Marchi et Damir Janigro

Epilepsia (Copenhagen), Vol.48(3), pp.505-516

03/2007

PMID: 17326793

Résumé

Anticonvulsants. Antiepileptics. Antiparkinson agents

Biological and medical sciences

Drug toxicity and drugs side effects treatment

Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy

Medical sciences

Miscellaneous (drug allergy, mutagens, teratogens...)

Nervous system (semeiology, syndromes)

Neurology

Neuropharmacology

Pharmacology. Drug treatments

1 Consultations de la notice

Titre: Development of a humanized in vitro blood-brain barrier model to screen for brain penetration of antiepileptic drugs
Créateurs - sans rôle: Luca Cucullo - Center for Cerebrovascular Research, Cleveland Clinic Lerner College of Medicine, United States
Mohammed Hossain - Cleveland Clinic Lerner College of Medicine
Ed Rapp - Flocel, Inc, Cleveland, Ohio, United States
Toby Manders - Center for Cerebrovascular Research, Cleveland Clinic Lerner College of Medicine, United States
Nicola Marchi - Center for Cerebrovascular Research, Cleveland Clinic Lerner College of Medicine, United States
Damir Janigro - Cleveland Clinic Lerner College of Medicine
Détails de publication: Epilepsia (Copenhagen), Vol.48(3), pp.505-516
Éditeur: Blackwell
Nombre de pages: 12
Identifiants: 99162965609311
Unité académique: Institut de Génomique Fonctionnelle - IGF
Langue: English
Type de ressource: Journal article