Design of peptide oxytocin antagonists with strikingly higher affinities and selectivities for the human oxytocin receptor than atosiban

Article de revue

Avec comité de lecture

Maurice Manning, Ling Ling Cheng, Stoytcho Stoev, Nga Ching Wo, W. Y Chan, Hazel H. Szeto, Thierry Durroux, Bernard Mouillac et Claude Barberis

Journal of peptide science, Vol.11(10), pp.593-608

10/2005

PMID: 15880385

Résumé

antagonists

atosiban

barusiban

human OT receptor

oxytocin

V1a receptor

vasopressin

1 Consultations de la notice

Titre: Design of peptide oxytocin antagonists with strikingly higher affinities and selectivities for the human oxytocin receptor than atosiban
Créateurs - sans rôle: Maurice Manning - Department of Biochemistry and Cancer Biology, Medical College of Ohio, Toledo, OH, USA
Ling Ling Cheng - Department of Biochemistry and Cancer Biology, Medical College of Ohio, Toledo, OH, USA
Stoytcho Stoev - Department of Biochemistry and Cancer Biology, Medical College of Ohio, Toledo, OH, USA
Nga Ching Wo - Department of Pharmacology, Weill Medical College of Cornell University, New York, NY, USA
W. Y Chan - Department of Pharmacology, Weill Medical College of Cornell University, New York, NY, USA
Hazel H. Szeto - Department of Pharmacology, Weill Medical College of Cornell University, New York, NY, USA
Thierry Durroux - Inserm
Bernard Mouillac - Inserm
Claude Barberis - Inserm
Détails de publication: Journal of peptide science, Vol.11(10), pp.593-608
Éditeur: John Wiley & Sons, Ltd
Nombre de pages: 16
Identifiants: 99139600609311
Unité académique: Institut de Génomique Fonctionnelle - IGF
Langue: English
Type de ressource: Journal article