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Design and synthesis of Indol-PHOX: a new class of modular phosphine–oxazoline ligands for palladium-catalyzed enantioselective decarboxylative allylation
Article de revue   Open Access   Avec comité de lecture

Design and synthesis of Indol-PHOX: a new class of modular phosphine–oxazoline ligands for palladium-catalyzed enantioselective decarboxylative allylation

Anzhela Karapetyan, Laura Borrel, Virginie Ratovelomanana-Vidal, Phannarath Phansavath, Tahar Ayad et David Virieux
RSC Advances, Vol.15(41), pp.34334-34339
2025

Résumé

A new class of modular phosphine–oxazoline ligands (Indol-PHOX) has been developed and successfully applied in Pd-catalyzed enantioselective decarboxylative allylation to access valuable α-allyl-α-fluoro ketones with yields up to 99% and 96% ee.

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