Design and Synthesis of Bis-Triazole-Linked Benzenesulfonamides as Selective Carbonic Anhydrase IX/XII Inhibitors with Chemosensitizing Activity

Eslam Roshdy; Ahmet Kilic; Muhamad Mustafa; Ismail Celik; Zeynep Betül Sarı; Ender Simsek; Alessio Nocentini; Simone Giovannuzzi; Claudiu Supuran; Özen Özensoy Güler; Jean-Yves Winum; Manabu Abe

doi:10.1021/acs.jmedchem.6c00547

Design and Synthesis of Bis-Triazole-Linked Benzenesulfonamides as Selective Carbonic Anhydrase IX/XII Inhibitors with Chemosensitizing Activity

Eslam Roshdy, Ahmet Kilic, Muhamad Mustafa, Ismail Celik, Zeynep Betül Sarı, Ender Simsek, Alessio Nocentini, Simone Giovannuzzi, Claudiu Supuran, Özen Özensoy Güler, …

Journal of Medicinal Chemistry

30/04/2026

: https://doi.org/10.1021/acs.jmedchem.6c00547

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: Design and Synthesis of Bis-Triazole-Linked Benzenesulfonamides as Selective Carbonic Anhydrase IX/XII Inhibitors with Chemosensitizing Activity
: Eslam Roshdy - Hiroshima University
Ahmet Kilic - Ankara Yıldırım Beyazıt University
Muhamad Mustafa - École Nationale Supérieure de Chimie de Montpellier
Ismail Celik - Erciyes University
Zeynep Betül Sarı - Education Training And Research
Ender Simsek - Education Training And Research
Alessio Nocentini - University of Florence
Simone Giovannuzzi - University of Florence
Claudiu Supuran - University of Florence
Özen Özensoy Güler
Jean-Yves Winum - Université de Montpellier, IBMM - Institut des Biomolécules Max Mousseron
Manabu Abe - Hiroshima University
: Journal of Medicinal Chemistry
: 99236019009311
: IBMM - Institut des Biomolécules Max Mousseron
: English
: Journal article
: hal-05610124