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Cytomegalovirus Infection With Retinitis After Brentuximab Vedotin Treatment for CD30+ Lymphoma
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Cytomegalovirus Infection With Retinitis After Brentuximab Vedotin Treatment for CD30+ Lymphoma

Jean-Jacques Tudesq, Laure Vincent, Julie Lebrun, Yosr Hicheri, Ludovic Gabellier, Timothé Busetto, Corinne Merle, Nathalie Fegueux, Patrice Ceballos, Philippe Quittet, …
Open forum infectious diseases, Vol.4(2), p.ofx091
01/04/2017
DOI: https://doi.org/10.1093/ofid/ofx091
PMID: 28638848

Résumé

Brief Report
Brentuximab vedotin is an antibody-conjugated chemotherapy targeting CD30 indicated in treatment of several lymphomas. We report the first 3 cases of cytomegalovirus severe infections with retinitis following this treatment. Evolution was favorable, but relapse occurred after treatment rechallenge. We suggest vigilance about cytomegalovirus in patients treated with brentuximab vedotin.

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