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Cover Feature: First Total Synthesis of Phytoprostanes with Prostaglandin‐Like Configuration, Evidence for Their Formation in Edible Vegetable Oils and Orienting Study of Their Biological Activity (Chem. Eur. J. 37/2021)
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Cover Feature: First Total Synthesis of Phytoprostanes with Prostaglandin‐Like Configuration, Evidence for Their Formation in Edible Vegetable Oils and Orienting Study of Their Biological Activity (Chem. Eur. J. 37/2021)

Jakub Smrček, Miroslav Hájek, Ondřej Hodek, Karel Čížek, Radek Pohl, Emanuela Jahn, Jean‐Marie Galano, Camille Oger, Thierry Durand, Josef Cvačka, …
Chemistry : a European journal, Vol.27(37), pp.9464-9464
02/07/2021

Résumé

oxidative stress phytoglandin phytoprostane total synthesis vegetable oil
Phytoglandins from the reaction flask enable their identification in Nature. Hypothetical plant‐based prostaglandin analogs were obtained by a 15‐step asymmetric total synthesis. They were applied as an analytical standard in a detailed LC‐MS/MS study confirming phytoglandin formation in autoxidized linolenic acid and in various edible vegetable oils in sizeable quantities. More information can be found in the Full Paper by U. Jahn et al. (DOI: 10.1002/chem.202100872).

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