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Copper-Catalyzed Hydroamination of Terminal Allenes
Article de revue   Avec comité de lecture

Copper-Catalyzed Hydroamination of Terminal Allenes

Remi Blieck, Janet Bahri, Marc Taillefer et Florian Monnier
Organic letters, Vol.18(6), pp.1482-1485
18/03/2016
PMID: 26959973

Résumé

Chemistry Chemistry, Organic Physical Sciences Science & Technology
The ligand-free copper-catalyzed hydroamination of allenes has been accomplished in the presence of cyclic secondary amines or anilines derivatives. This novel methodology undergoes the selective generation of (E)-allylamines under smooth conditions with total regio- and stereoselectivity.

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