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Copper-Catalyzed Direct Synthesis of Benzamides from Alcohols and Amines
Journal article   Peer reviewed

Copper-Catalyzed Direct Synthesis of Benzamides from Alcohols and Amines

Xavier Bantreil, Clément Fleith, Jean Martinez and Frédéric Lamaty
Angewandte Chemie, Vol.4, pp.1922-1925
2012

Abstract

Ready, steady, copper! The efficient copper-catalyzed formation of amides, from benzylic alcohols and hydrochloride salts of primary- and secondary amines, uses cheap and readily available copper oxide, as well as tert-butylhydroperoxide (TBHP) as an oxidant.
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