Logo image
Sign in
Copper-Catalyzed Arylation of Nitrogen Heterocycles from Anilines under Ligand-Free Conditions
Journal article   Peer reviewed

Copper-Catalyzed Arylation of Nitrogen Heterocycles from Anilines under Ligand-Free Conditions

Dounia Toummini, Anis Tlili, Julien Bergès, Fouad Ouazzani and Marc Taillefer
Chemistry - A European Journal, Vol.20(45), pp.14619-14625
11/2014

Abstract

Abstract: The arylation of pyrazole and derivatives can beachieved by coupling arenediazonium species (formedin situ from anilines) by using a catalytic system that em-ploys low-toxicity and inexpensive copper metal undervery mild and ligand-free conditions (T = 20 8C). Fromother nitrogen heterocycles, the presence of an additive(NBu4I) significantly improves the efficiency of the catalyticsystem. These results represent the first examples of CÀNbond formation from arenediazonium species.
url
Find in HALView

Metrics

1 Record Views

Details

Logo image