Résumé
First clinical results are also promising in patients with acute coronary syndromes.2 Perhaps because most patients with acute pericarditis are fairly young and have few comorbidities, adverse effects from colchicine for this indication have been surprisingly rare and mild. [...]a recent large study found no increase in abortions or congenital malformations among offspring of women treated with colchicine for familial Mediterranean fever, compared to those of pregnant women with or without the disorder who had not taken colchicine.7 Suggested contraindications: * Avoid if possible: protease inhibitors, statins, cyclosporine, anticoagulants * Contraindicated: Macrolide (telithromycin, azythromycin, clarithromycin(Drug information on clarithromycin), dirithromycin(Drug information on dirithromycin), erythromycin(Drug information on erythromycin), josamycin(Drug information on josamycin), midecamycin, roxithromycin(Drug information on roxithromycin), troleandromycin, spiramycin(Drug information on spiramycin)), pristinamycine, verapamil(Drug information on verapamil) * Creatinine clearance < 30 mL/min (recent dosage) * Severe hepatic dysfunction * Uncontrolled or unexplained anemia, thrombocytopenia, or leucopenia * If possible: