Abstract
Odile Grynszpan-Winograd (1938-2023) was a French ultrastructural morphologist who worked in Paris in the second half of the twentieth century. She devoted her scientific life to the study of the adrenal gland anatomy. Through her countless electron microscopy images, in which she was undeniably an expert, Odile Grynszpan-Winograd pioneered the visualization of the liberation of chromaffin secretory granule content, providing an unequivocal anatomical demonstration of the exocytosis process. This seminal finding constituted a major advance in deciphering the stimulus-secretion coupling of the adrenal medullary tissue. By combining transmission electron microscopy with cryofracture, Odile Grynszpan-Winograd was also the first to illustrate gap junction plaques between chromaffin cells. However Odile Grynszpan-Winograd did not receive the entire benefit of her contributions, particularly with regard to the vesicular secretion of catecholamines, a subject that has been in debate for many years.