Chemoenzymatic synthesis of the two enantiomers of 7-azatryptophan

L Lecointe; V Rolland-Fulcrand; M.L Roumestant; Ph Viallefont; J Martinez

doi:10.1016/S0957-4166(98)00130-X

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Chemoenzymatic synthesis of the two enantiomers of 7-azatryptophan

Journal article

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Chemoenzymatic synthesis of the two enantiomers of 7-azatryptophan

L Lecointe, V Rolland-Fulcrand, M.L Roumestant, Ph Viallefont and J Martinez

Tetrahedron: Asymmetry, Vol.9(10), pp.1753-1758

05/1998

DOI: https://doi.org/10.1016/S0957-4166(98)00130-X

Abstract

7-Azatryptophan is an unnatural α-amino acid with a very potent fluorescent activity. It is used as a vehicle for probing the structure and dynamics of proteins and peptides. Diastereoselective alkylation, diastereoselective protonation and enzymatic resolution have been tested for preparing enantiomerically pure 7-azatryptophan.

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Title: Chemoenzymatic synthesis of the two enantiomers of 7-azatryptophan
Creators - without role: L Lecointe - Laboratoire des Amino-acides Peptides et Protéines
V Rolland-Fulcrand - Institut des Biomolécules Max Mousseron
M.L Roumestant - Laboratoire des Amino-acides Peptides et Protéines
Ph Viallefont - Laboratoire des Amino-acides Peptides et Protéines
J Martinez - Université de Montpellier, Institut des Biomolécules Max Mousseron - IBMM
Publication Details: Tetrahedron: Asymmetry, Vol.9(10), pp.1753-1758
Identifiers: 9944655909311
Academic Unit: Institut des Biomolécules Max Mousseron - IBMM
Language: English
Resource Type: Journal article
Local Fields: hal-04651169