Characterizing the chromosomes of the platypus (Ornithorhynchus anatinus)

Daniel McMillan; Pat Miethke; Amber E. Alsop; Willem Rens; Patricia O'Brien; Vladimir Trifonov; Frederic Veyrunes; Kyriena Schatzkamer; Colin L. Kremitzki; Tina Graves; Wesley Warren; Frank Grutzner; Malcolm A. Ferguson-Smith; Jennifer A. Marshall Graves

doi:10.1007/s10577-007-1186-2

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Characterizing the chromosomes of the platypus (Ornithorhynchus anatinus)

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Characterizing the chromosomes of the platypus (Ornithorhynchus anatinus)

Daniel McMillan, Pat Miethke, Amber E. Alsop, Willem Rens, Patricia O'Brien, Vladimir Trifonov, Frederic Veyrunes, Kyriena Schatzkamer, Colin L. Kremitzki, Tina Graves, …

Chromosome research, Vol.15(8), pp.961-974

01/12/2007

DOI: https://doi.org/10.1007/s10577-007-1186-2

PMID: 18185982

Résumé

Biochemistry & Molecular Biology

Genetics & Heredity

Life Sciences & Biomedicine

Science & Technology

Like the unique platypus itself, the platypus genome is extraordinary because of its complex sex chromosome system, and is controversial because of difficulties in identification of small autosomes and sex chromosomes. A 6-fold shotgun sequence of the platypus genome is now available and is being assembled with the help of physical mapping. It is therefore essential to characterize the chromosomes and resolve the ambiguities and inconsistencies in identifying autosomes and sex chromosomes. We have used chromosome paints and DAPI banding to identify and classify pairs of autosomes and sex chromosomes. We have established an agreed nomenclature and identified anchor BAC clones for each chromosome that will ensure unambiguous gene localizations.

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Détails

Titre: Characterizing the chromosomes of the platypus (Ornithorhynchus anatinus)
Créateurs - sans rôle: Daniel McMillan - Australian Natl Univ, Res Sch Biol Sci, Comparat Genom Grp, Canberra, ACT 2601, Australia
Pat Miethke - Australian Natl Univ, Res Sch Biol Sci, Comparat Genom Grp, Canberra, ACT 2601, Australia
Amber E. Alsop - Australian Natl Univ, Res Sch Biol Sci, Comparat Genom Grp, Canberra, ACT 2601, Australia
Willem Rens - Univ Cambridge, Dept Vet Med, Ctr Vet Med, Mol Cytogenet Lab, Cambridge CB3 0ES, England
Patricia O'Brien - Univ Cambridge, Dept Vet Med, Ctr Vet Med, Mol Cytogenet Lab, Cambridge CB3 0ES, England
Vladimir Trifonov - Univ Cambridge, Dept Vet Med, Ctr Vet Med, Mol Cytogenet Lab, Cambridge CB3 0ES, England
Frederic Veyrunes - Australian Natl Univ, Res Sch Biol Sci, Comparat Genom Grp, Canberra, ACT 2601, Australia
Kyriena Schatzkamer - Washington Univ, Sch Med, Genome Sequencing Ctr, St Louis, MO 63108 USA
Colin L. Kremitzki - Washington Univ, Sch Med, Genome Sequencing Ctr, St Louis, MO 63108 USA
Tina Graves - Washington Univ, Sch Med, Genome Sequencing Ctr, St Louis, MO 63108 USA
Wesley Warren - Washington Univ, Sch Med, Genome Sequencing Ctr, St Louis, MO 63108 USA
Frank Grutzner - The University of Adelaide
Malcolm A. Ferguson-Smith - University of Cambridge
Jennifer A. Marshall Graves - Australian Natl Univ, Res Sch Biol Sci, Comparat Genom Grp, Canberra, ACT 2601, Australia
Détails de publication: Chromosome research, Vol.15(8), pp.961-974
Éditeur: Springer Nature
Nombre de pages: 14
Identifiants: 99146376809311
Unité académique: Institut des Sciences de l'Evolution - Montpellier - ISEM
Langue: English
Type de ressource: Journal article