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Characterization of the mouse Cblc/Cbl3 gene
Article de revue   Avec comité de lecture

Characterization of the mouse Cblc/Cbl3 gene

Frédéric Fiore, Vincent Ollendorff et Daniel Birnbaum
Biochemical and biophysical research communications, Vol.280(1), pp.182-187
12/01/2001
PMID: 11162497

Résumé

Life Sciences
The mouse Cblc/Cbl3 gene was cloned and characterized. It comprises 12 exons and encodes a putative protein of 496 amino acid residues which shares an overall 67% identity with its human ortholog; it also shares 70% of amino acid identity with mouse CBL over their conserved SH2 and Ring finger domains. Mouse Cblc mRNA is expressed in embryo and adult tissues and has a rather ubiquitous distribution.

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