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Characterization of peptides released from gluten-free climate-smart cowpea-based pasta during gastric and intestinal in vitro digestion
Article de revue scientifique   Open Access   Avec comité de lecture

Characterization of peptides released from gluten-free climate-smart cowpea-based pasta during gastric and intestinal in vitro digestion

P. Pinel, Mélina Robert, Julien Jardin, Olivia Ménard, Amélie Deglaire, V. Micard et Claire Bourlieu-Lacanal
Food Chemistry, Vol.505
03/2026

Résumé

Allergenicity Proteins wheat semolina Durum leaves Amaranth Teff
Four nutritionally optimized cowpea-based pasta incorporating or not teff and/or amaranth leaves underwent in vitro static gastro-intestinal digestion using the Infogest model. The aim of this study was to characterize the peptides released at the end of the gastric and intestinal phase of cowpea-based pasta compared to wheat-based pasta controls with an increasing fiber content, using SDS-PAGE and mass spectrometry. At end of intestinal phase, the four cowpea-based pasta presented slightly lower peptides number of similar size compared to wheat-based pasta, which could indicate a lower proteolysis. Additionally, no significant difference in origin of peptide profile was observed with teff or amaranth leaf additions within cowpea-based pasta, nor with the increase of fiber within wheat-based pasta. Peptide released from cowpea-based pasta mainly comes from cowpea proteins, and especially globulins “RmlC-jelly roll fold” and “11S-seed storage protein”. Vigilance is required for these globulin which have putative allergenic epitopes on their sequences.

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