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Characterization of an expanded subpopulation of large granular lymphocytes in a patient with rheumatoid arthritis
Article de revue scientifique

Characterization of an expanded subpopulation of large granular lymphocytes in a patient with rheumatoid arthritis

Bernard Combe, Monique Andary, Jean Caraux, Pierre Baldet, Françoise Barchechath, Jacques Clot et Jacques Sany
Arthritis and rheumatism, Vol.29(5), p.675-679
05/1986
PMID: 3718558

Résumé

We describe a rheumatoid arthritis patient who was found to have chronic T cell lymphocytosis and neutropenia. She had an increased number of lymphocytes in the peripheral blood, bone marrow, and liver, and the expanded lymphocyte subset consisted of large granular lymphocytes with a homogeneous phenotype. Of the previously described patients with these large granular lymphocytes, almost one‐fourth have had rheumatoid arthritis.

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