Case Report: Persistency Pneumococcal Polysaccharide in Cerebrospinal Fluid During a Post Pneumococcal Chronic Aseptic Meningitis: Coincidental or (Auto-)Inflammatory Embers

Manon Ladeveze; Yann Dumont; G. Boursier; Frederic Batteux; Perrine Mahe; Aurelie Bensimon Borrull; Guillaume Sarrabay; Karine Bollore; Edouard Tuaillon; Sylvain Godreuil; Eric Jeziorski

doi:10.3389/fped.2022.762457

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Case Report: Persistency Pneumococcal Polysaccharide in Cerebrospinal Fluid During a Post Pneumococcal Chronic Aseptic Meningitis: Coincidental or (Auto-)Inflammatory Embers

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Case Report: Persistency Pneumococcal Polysaccharide in Cerebrospinal Fluid During a Post Pneumococcal Chronic Aseptic Meningitis: Coincidental or (Auto-)Inflammatory Embers

Manon Ladeveze, Yann Dumont, G. Boursier, Frederic Batteux, Perrine Mahe, Aurelie Bensimon Borrull, Guillaume Sarrabay, Karine Bollore, Edouard Tuaillon, Sylvain Godreuil, …

Frontiers in Pediatrics, Vol.10

2022

DOI: https://doi.org/10.3389/fped.2022.762457

Abstract

pneumococcal meningitis

pneumococcal cell wall components

aseptic meningitis

chronic aseptic meningitis

innate immunity

We report the case of a 9-months-old boy that has presented a steroid-dependent post-pneumococcal chronic aseptic meningitis was associated with persistence of pneumococcal cell wall components in cerebrospinal fluid during more than 20 months. Suggesting that this antigenic persistence could be involved in post-infectious manifestations through innate immunity response.

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Title: Case Report: Persistency Pneumococcal Polysaccharide in Cerebrospinal Fluid During a Post Pneumococcal Chronic Aseptic Meningitis: Coincidental or (Auto-)Inflammatory Embers
Creators - without role: Manon Ladeveze - Centre Hospitalier Universitaire de Montpellier
Yann Dumont - Département de génétique médicale, maladies rares et médecine personnalisée [CHU Montpellier]
G. Boursier - Centre Hospitalier Universitaire de Montpellier
Frederic Batteux - Hôpital Cochin
Perrine Mahe - Centre Hospitalier Universitaire de Montpellier
Aurelie Bensimon Borrull - Hôpital Cochin
Guillaume Sarrabay - Département de génétique médicale, maladies rares et médecine personnalisée [CHU Montpellier]
Karine Bollore - Université de Montpellier, Pathogenesis and Control of Chronic and Emerging Infections - PCCEI
Edouard Tuaillon - Université de Montpellier, Pathogenesis and Control of Chronic and Emerging Infections - PCCEI
Sylvain Godreuil - Maladies Infectieuses et Vecteurs: Écologie, Génétique, Évolution et Contrôle
Eric Jeziorski - Université de Montpellier, Pathogenesis and Control of Chronic and Emerging Infections - PCCEI
Publication Details: Frontiers in Pediatrics, Vol.10
Identifiers: 9941131009311
Academic Unit: Maladies Infectieuses et Vecteurs : Ecologie, Génétique, Evolution et Contrôle - MIVEGEC; Pathogenesis and Control of Chronic and Emerging Infections - PCCEI
Language: English
Resource Type: Journal article
Local Fields: hal-03980113