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BrdU incorporation in multiparameter flow cytometry: A new cell cycle assessment approach in multiple myeloma
Journal article   Open access   Peer reviewed

BrdU incorporation in multiparameter flow cytometry: A new cell cycle assessment approach in multiple myeloma

Guilhem Requirand, Nicolas Robert, Stéphanie Boireau, Laure Vincent, Anja Seckinger, Salaheddine Bouhya, Patrice Ceballos, Guillaume Cartron, Dirk Hose, Bernard Klein, …
Cytometry Part B: Clinical Cytometry
12/11/2018
DOI: https://doi.org/10.1002/cyto.b.21730
PMID: 30417559

Abstract

cytometry monoclonal multiparameter analysis prognosis proliferation
Mutiple myeloma (MM) is a neoplasia characterized by the accumulation of malignant plasma cells (PC) in the bone marrow. Although proliferation markers have been studied in MM, none of the current staging systems include them. Moreover, approaches used to analyze proliferation do not separate MM cells (MMCs) from normal PC.
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