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Brain Damage and Motor Cortex Impairment in Chronic Obstructive Pulmonary Disease: Implication of Nonrapid Eye Movement Sleep Desaturation
Article de revue   Open Access

Brain Damage and Motor Cortex Impairment in Chronic Obstructive Pulmonary Disease: Implication of Nonrapid Eye Movement Sleep Desaturation

Francois Alexandre, Nelly Heraud, Anthony M J Sanchez, Emilie Tremey, Nicolas Oliver, Philippe Guérin et Alain Varray
Sleep, Vol.39(2), pp.327 - 335
01/02/2016
DOI: https://doi.org/10.5665/sleep.5438
PMID: 26446126

Résumé

central nervous system cerebral cortex electromyography muscle weakness voluntary activation central nervous system Adult Aged Motor Cortex Muscle Contraction Muscle Strength Oxygen Polysomnography Prevalence Pulmonary Disease, Chronic Obstructive Quadriceps Muscle S100 Calcium Binding Protein beta Subunit Sleep Aged, 80 and over Biomarkers Brain Injuries Female Humans Male Middle Aged
Nonrapid eye movement (NREM) sleep desaturation may cause neuronal damage due to the withdrawal of cerebrovascular reactivity. The current study (1) assessed the prevalence of NREM sleep desaturation in nonhypoxemic patients with chronic obstructive pulmonary disease (COPD) and (2) compared a biological marker of cerebral lesion and neuromuscular function in patients with and without NREM sleep desaturation.

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