Biomarker counseling, disclosure of diagnosis and follow-up in patients with mild cognitive impairment: A European Alzheimer's disease consortium survey

Kristian S. Frederiksen; Thomas R. Nielsen; Ildebrando Appollonio; Birgitte Bo Andersen; Mario Riverol; Merce Boada; Mathieu Ceccaldi; Bruno Dubois; Sebastiaan Engelborghs; Lutz Froelich; Lucrezia Hausner; Audrey Gabelle; Tomasz Gabryelewicz; Timo Grimmer; Bernard Hanseeuw; Jakub Hort; Jacques Hugon; Vesna Jelic; Anne Koivisto; Milica G. Kramberger; Thibaud Lebouvier; Alberto Lleo; Alexandre de Mendonca; Flavio Nobili; Pierre-Jean Ousset; Robert Perneczky; Marcel Olde Rikkert; David Robinson; Olivier Rouaud; Elisabet Sanchez; Isabel Santana; Nikolaos Scarmeas; Katerina Sheardova; Stephanie Sloan; Luiza Spiru; Elka Stefanova; Latchezar Traykov; Gorsev Yener; Gunhild Waldemar

doi:10.1002/gps.5427

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Biomarker counseling, disclosure of diagnosis and follow-up in patients with mild cognitive impairment: A European Alzheimer's disease consortium survey

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Biomarker counseling, disclosure of diagnosis and follow-up in patients with mild cognitive impairment: A European Alzheimer's disease consortium survey

Kristian S. Frederiksen, Thomas R. Nielsen, Ildebrando Appollonio, Birgitte Bo Andersen, Mario Riverol, Merce Boada, Mathieu Ceccaldi, Bruno Dubois, Sebastiaan Engelborghs, Lutz Froelich, …

International journal of geriatric psychiatry, Vol.36(2), pp.324-333

02/2021

DOI: https://doi.org/10.1002/gps.5427

PMID: 32896040

Résumé

Geriatrics & Gerontology

Gerontology

Life Sciences & Biomedicine

Psychiatry

Science & Technology

Objectives Mild cognitive impairment (MCI) is associated with an increased risk of further cognitive decline, partly depending on demographics and biomarker status. The aim of the present study was to survey the clinical practices of physicians in terms of biomarker counseling, management, and follow-up in European expert centers diagnosing patients with MCI. Methods An online email survey was distributed to physicians affiliated with European Alzheimer's disease Consortium centers (Northern Europe: 10 centers; Eastern and Central Europe: 9 centers; and Southern Europe: 15 centers) with questions on attitudes toward biomarkers and biomarker counseling in MCI and dementia. This included postbiomarker counseling and the process of diagnostic disclosure of MCI, as well as treatment and follow-up in MCI. Results The response rate for the survey was 80.9% (34 of 42 centers) across 20 countries. A large majority of physicians had access to biomarkers and found them useful. Pre- and postbiomarker counseling varied across centers, as did practices for referral to support groups and advice on preventive strategies. Less than half reported discussing driving and advance care planning with patients with MCI. Conclusions The variability in clinical practices across centers calls for better biomarker counseling and better training to improve communication skills. Future initiatives should address the importance of communicating preventive strategies and advance planning.

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Titre: Biomarker counseling, disclosure of diagnosis and follow-up in patients with mild cognitive impairment: A European Alzheimer's disease consortium survey
Créateurs - sans rôle: Kristian S. Frederiksen - Univ Copenhagen, Danish Dementia Res Ctr, Dept Neurol, Rigshosp, Copenhagen, Denmark
Thomas R. Nielsen - Univ Copenhagen, Danish Dementia Res Ctr, Dept Neurol, Rigshosp, Copenhagen, Denmark
Ildebrando Appollonio - Univ Milano Bicocca, Sch Med & Surg, Milan, Italy
Birgitte Bo Andersen - Univ Copenhagen, Danish Dementia Res Ctr, Dept Neurol, Rigshosp, Copenhagen, Denmark
Mario Riverol - Univ Navarra, Clin Univ Navarra, Dept Neurol, Madrid, Spain
Merce Boada - Fundació ACE
Mathieu Ceccaldi - CHU Timone, APHM, Dept Neurol & Neuropsychol, Marseille, France
Bruno Dubois - Salpetriere Univ Hosp, Alzheimer Res Ctr IM2A, Paris, France
Sebastiaan Engelborghs - Inst Born Bunge, Reference Ctr Biol Markers Dementia BIODEM, Antwerp, Belgium
Lutz Froelich - Heidelberg Univ, Cent Inst Mental Hlth, Dept Geriatr Psychiat, Mannheim, Germany
Lucrezia Hausner - Heidelberg Univ, Cent Inst Mental Hlth, Dept Geriatr Psychiat, Mannheim, Germany
Audrey Gabelle - Univ Montpellier, Memory Resources & Res Ctr, Dept Neurol, Gui Chauliac Hosp,Montpellier Univ Hosp, Montpellier, France
Tomasz Gabryelewicz - Mossakowski Med Res Ctr PAN, Dept Neurodegenerat Disorders, Warsaw, Poland
Timo Grimmer - Tech Univ Munich, Sch Med, Klinikum Rechts Isar, Dept Psychiat & Psychotherapy, Munich, Germany
Bernard Hanseeuw - Catholic Univ Louvain, Inst Neurosci, Dept Neurol, Clin Univ St Luc, Brussels, Belgium
Jakub Hort - Charles Univ Prague, Memory Clin, Dept Neurol, Fac Med 2,Motol Univ Hosp, Prague, Czech Republic
Jacques Hugon - Univ Paris, Lariboisiere Hosp Paris, Ctr Cognit Neurol, Paris, France
Vesna Jelic - Karolinska Univ Hosp Huddinge, Clin Cognit Disorders, Theme Aging, Stockholm, Sweden
Anne Koivisto - Univ Eastern Finland, Kuopio Univ Hosp, Dept Neurol, Kuopio, Finland
Milica G. Kramberger - Univ Med Ctr Ljubljana, Ctr Cognit Impairments, Ljubljana, Slovenia
Thibaud Lebouvier - Lille 2 Univ Hlth & Law, Pole Neurol, Lille, France
Alberto Lleo - Hosp Santa Creu & Sant Pau, Neurol Dept, Barcelona, Spain
Alexandre de Mendonca - Univ Lisbon, Fac Med, Lisbon, Portugal
Flavio Nobili - University of Genoa
Pierre-Jean Ousset - Toulouse Univ Hosp, Clin Res Ctr, Memory Clin, Toulouse, France
Robert Perneczky - Ludwig Maximilians Univ Munchen, Univ Hosp, Dept Psychiat & Psychotherapy, Munich, Germany
Marcel Olde Rikkert - Radboud Univ Nijmegen, Radboudumc Alzheimer Ctr, Dept Geriatr, Med Ctr, Nijmegen, Netherlands
David Robinson - St James Hosp, Memory Clin, Dublin, Ireland
Olivier Rouaud - Vaud Univ Hosp, Leenaards Memory Ctr, Dept Clin Neurosci, Lausanne, Switzerland
Elisabet Sanchez - Hosp Univ Ramon & Cajal, Serv Geriatria, Madrid, Spain
Isabel Santana - University of Coimbra
Nikolaos Scarmeas - National and Kapodistrian University of Athens
Katerina Sheardova - St Annes Univ Hosp, Memory Ctr ICRC, Int Clin Res Ctr, Brno, Czech Republic
Stephanie Sloan - Ninewells Hosp, Neuroprogress Disorders & Dementia Network, Dundee, Scotland
Luiza Spiru - Carol Davila Univ Med & Pharm, Geriatr Gerontol & Old Age Psychiat Alzheimer Uni, Clin Dept, Bucharest, Romania
Elka Stefanova - Univ Belgrade, Fac Med, Clin Ctr Serbia, Neurol Clin, Belgrade, Serbia
Latchezar Traykov - UH Alexandrovska, Dept Neurol, Sofia, Bulgaria
Gorsev Yener - Dokuz Eylul Univ, Dept Neurosci, Med Sch, Izmir, Turkey
Gunhild Waldemar - Univ Copenhagen, Danish Dementia Res Ctr, Dept Neurol, Rigshosp, Copenhagen, Denmark
Détails de publication: International journal of geriatric psychiatry, Vol.36(2), pp.324-333
Éditeur: Wiley
Nombre de pages: 10
Identifiants: 99140208909311
Unité académique: Institut des Neurosciences de Montpellier - INM
Langue: English
Type de ressource: Journal article