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Association between hydroxocobalamin administration and acute kidney injury after smoke inhalation: a multicenter retrospective study
Journal article   Open access   Peer reviewed

Association between hydroxocobalamin administration and acute kidney injury after smoke inhalation: a multicenter retrospective study

François Dépret, Clement Hoffmann, Laura Daoud, Camille Thieffry, Laure Monplaisir, Jules Creveaux, Djillali Annane, Erika Parmentier, Daniel Mathieu, Sandrine Wiramus, …
Critical Care, Vol.23(1)
12/2019
PMID: 31870461

Abstract

Hydroxocobalamin Intensive care unit Smoke inhalation Mortality Acute kidney injury Burn Hydroxocobalamin
The use of hydroxocobalamin has long been advocated for treating suspected cyanide poisoning after smoke inhalation. Intravenous hydroxocobalamin has however been shown to cause oxalate nephropathy in a single-center study. The impact of hydroxocobalamin on the risk of acute kidney injury (AKI) and survival after smoke inhalation in a multicenter setting remains unexplored.
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