Are antiphospholipid antibodies associated with thrombotic complications in critically ill COVID-19 patients?

Virginie Siguret; Sebastian Voicu; Marie Neuwirth; Maxime Delrue; Etienne Gayat; Alain Stépanian; Bruno Mégarbane

doi:10.1016/j.thromres.2020.07.016

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Are antiphospholipid antibodies associated with thrombotic complications in critically ill COVID-19 patients?

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Are antiphospholipid antibodies associated with thrombotic complications in critically ill COVID-19 patients?

Virginie Siguret, Sebastian Voicu, Marie Neuwirth, Maxime Delrue, Etienne Gayat, Alain Stépanian et Bruno Mégarbane

Thrombosis research, Vol.195, pp.74-76

01/11/2020

DOI: https://doi.org/10.1016/j.thromres.2020.07.016

PMID: 32663703

Résumé

Anti-β2-glycoprotein-I

Anticardiolipin

COVID-19

Lupus anticoagulant

Thrombosis

•The prevalence of aPL antibodies is poorly documented in ICU COVID-19 patients.•LA based on dRVVT system was positive in 85% of critically ill COVID-19 patients.•LA was not associated with thrombotic complications.•The prevalence of elevated anticardiolipin IgG/M/anti-beta2-GPI IgG was of 12%.

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Détails

Titre: Are antiphospholipid antibodies associated with thrombotic complications in critically ill COVID-19 patients?
Créateurs - sans rôle: Virginie Siguret - Laboratory of Hematology, Lariboisière Hospital, Paris University, Paris, France
Sebastian Voicu - Department of Medical and Toxicological Critical Care, Lariboisière Hospital, Paris University, Paris, France
Marie Neuwirth - Laboratory of Hematology, Lariboisière Hospital, Paris University, Paris, France
Maxime Delrue - Laboratory of Hematology, Lariboisière Hospital, Paris University, Paris, France
Etienne Gayat - Department of Anesthesiology and Critical Care, Lariboisière Hospital, Paris University, Paris, France
Alain Stépanian - Laboratory of Hematology, Lariboisière Hospital, Paris University, Paris, France
Bruno Mégarbane - Department of Medical and Toxicological Critical Care, Lariboisière Hospital, Paris University, Paris, France
Détails de publication: Thrombosis research, Vol.195, pp.74-76
Éditeur: Elsevier Ltd
Nombre de pages: 3
Identifiants: 99148668109311
Unité académique: Physiologie et Médecine Expérimentale du coeur et des muscles - PhyMedExp
Langue: English
Type de ressource: Journal article