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Anomalous reactivity of diphenylhydroxymethylphosphine oxide in the synthesis of a phosphorylated ether by oxa- Michael reaction
Journal article   Peer reviewed

Anomalous reactivity of diphenylhydroxymethylphosphine oxide in the synthesis of a phosphorylated ether by oxa- Michael reaction

Henri-Jean Cristau and David Null Virieux
Tetrahedron Letters, Vol.40(4), pp.703-706
1999

Abstract

Vinylic phosphorus compounds were found to react as Michael olefins with alcohols in basic catalytic conditions. Several phosphorylated polyethers were obtained in such a way. In analogous conditions, the hydroxymethylphosphine oxide used as alcoholic reagent looses formaldehyde leading to 1,2-diphosphorus compound formation.
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