Résumé
Drug hypersensitivity reactions are a daily worry for the clinicians, in particular anaphylactic reactions. The tools allowing a definite diagnosis are few and poorly validated. They include a thorough clinical history, standardized skin tests, reliable biological tests, and sometimes drug provocation tests. These tools are currently being evaluated by the European Network of Drug Allergy, under the aegis of the EAACI drug hypersensitivity group of interest.